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Dysport 500 Units from the French manufacturer Ipsen Pharma is derived from pure botulinum toxin produced by a specific type of bacteria. The company employs a unique technology to refine and purify the toxin, ensuring its safety for use in reducing wrinkles and folds caused by facial expressions. When applied into the skin, it blocks certain proteins in the nerve cells, preventing nerve endings from receiving signals from the brain. As a result, the muscles become insensitive and stop contracting, leading to gradual relaxation and reduced tension.
Main Benefits of Dysport 500
Fast Results
Visible smoothing typically appears within 2–5 days.
Natural Expression
Softens lines while maintaining natural facial movement.
Long-Lasting Effects
Results usually last 3–6 months.
Versatile Use
Suitable for frown lines, crow’s feet, and other areas.
Well-Studied Formula
Clinically tested in 120+ countries with a strong safety profile.
Smooth Diffusion
Made under strict standards and KFDA-approved for safety.
Indications
-
Cosmetic Facial Rejuvenation & Line Softening
Dysport 500 is used to reduce dynamic facial lines—such as frown lines, forehead lines, and crow’s feet—by relaxing the facial muscles responsible for these wrinkles. -
Multi-Area Cosmetic Treatments
The 500-unit vial allows professionals to address several aesthetic zones in one session, offering flexibility for broader facial rejuvenation. -
Common Facial Treatment Areas
Frequently applied to cosmetic areas including glabellar lines, forehead lines, crow’s feet, bunny lines, chin dimpling, and jawline tension points. -
Enhancing Facial Symmetry & Softening Expression
Used cosmetically to minimize strong muscle activity that affects facial balance or creates harsh expression lines, helping achieve a smoother, more refined look.
How is Dysport made
Dysport 500 is manufactured by Ipsen Pharma in France using a controlled biopharmaceutical process designed to produce a highly purified form of botulinum toxin type A. The steps are:
1. Culturing the Botulinum Strain
A specific strain of Clostridium botulinum is grown under controlled laboratory conditions to produce the neurotoxin.
2. Purification of the Toxin
The toxin is isolated and refined through multiple purification steps. Ipsen uses a proprietary process to remove unwanted bacterial proteins and achieve a consistent potency.
3. Stabilization With Excipients
The purified toxin is blended with stabilizing ingredients — such as human serum albumin and lactose — which protect the toxin structure and keep it stable until reconstitution.
4. Sterile Filling & Freeze-Drying
The formula is filled into sterile vials under aseptic conditions and then freeze-dried (lyophilized) to create a stable powder form.
5. Stringent Quality Control
Each batch is tested for purity, potency, safety, sterility, and stability according to international GMP (Good Manufacturing Practice) standards.
6. Cold-Chain Packaging
Once approved, Dysport is sealed, labeled, and maintained under cold-chain conditions to preserve its integrity during storage and transport.
What Dysport 500 is made of
-
Clostridium Botulinum Toxin Type A (500U)
A purified neurotoxic protein that blocks nerve signals in targeted muscles, helping soften the appearance of dynamic facial lines. -
Human Serum Albumin (0.5 mg)
A plasma-derived protein used as a stabilizer to protect the toxin’s structure and maintain its effectiveness after reconstitution. -
Lactose (125 mg)
A stabilizing excipient that supports the freeze-dried form of the product and helps preserve its integrity during storage.
Mechanism of action
Dysport 500 works by temporarily reducing the activity of specific facial muscles responsible for creating dynamic expression lines. When injected into targeted areas, the formula interacts with the nerve endings that control muscle movement, limiting the signals that tell those muscles to contract.
As the treated muscles become less active, the skin above them begins to relax. This softening of muscle activity gradually reduces the appearance of wrinkles formed by repeated expressions such as frowning, squinting, or raising the eyebrows.
The effects do not occur immediately. The smoothing process typically begins within 2 to 5 days and continues to improve as the muscles settle. Results last 3 to 6 months, depending on individual factors and aesthetic goals, after which muscle activity naturally returns.
Why does Dysport 500 look Empty? (Video Explanation)
Product preparation
Before use, Dysport 500 must be reconstituted with preservative-free 0.9% sterile saline (sodium chloride injection) to prepare it for cosmetic procedures. It is supplied as a fine, freeze-dried powder in a colorless, transparent glass vial containing 500 units. The vial may appear nearly empty, which is normal for this product.
Preparation Steps:
Remove the Dysport 500 vial from refrigeration and visually inspect it. The powder should appear as a fine, almost invisible layer on the bottom or walls of the vial.
Using a sterile syringe, slowly add the desired amount of preservative-free 0.9% saline into the vial (refer to the dilution chart for the 500-unit vial).
Gently swirl the vial to dissolve the powder — do not shake vigorously. The solution should become clear and colorless.
Use the reconstituted solution within 24 hours and store it in a refrigerator at 2–8°C until use. Do not freeze after reconstitution.
How to dilute Dysport 500?
Dysport 500 comes in a vial containing a fine, freeze-dried powder with 500 units of Botulinum toxin type A that must be diluted with preservative-free 0.9% sterile saline before use.
Note: The powder is extremely fine, so the vial may look empty. This is normal — all units are present.
Step-by-Step Dilution Instructions:
Begin by visually inspecting the Dysport 500 vial. The powder will appear as a thin, nearly invisible layer — this is normal.
Draw the selected amount of preservative-free 0.9% Sodium Chloride (saline) into a sterile syringe, based on the dilution chart above.
Slowly inject the saline into the vial. Allow the vacuum inside the vial to pull in the solution naturally.
Gently swirl the vial to mix. Do not shake or stir aggressively. The solution should become clear and colorless.
Store the reconstituted solution in a refrigerator at 2–8°C and use within 24 hours. Do not freeze after reconstitution.
Treatment areas
- Glabellar Lines (Frown Lines)
Commonly used to soften the vertical lines between the eyebrows caused by repeated frowning. - Forehead Lines
Helps relax the frontalis muscle to smooth horizontal forehead creases. - Crow’s Feet
Targets the outer corners of the eyes to reduce fine lines that appear with smiling and squinting. - Bunny Lines
Applied along the sides of the nose to soften wrinkles formed during scrunching or smiling. - Chin Dimpling
Used to smooth an uneven, overactive chin surface caused by mentalis muscle movement. - Jawline Tension (Masseter Area)
Helps reduce the appearance of bulkiness from strong masseter muscles, contributing to a slimmer-looking lower face.
Dosage and technique
Dysport 500 is reconstituted based on the desired dilution, and the final dosing amount depends on the treatment area and the client’s aesthetic goals. Professionals typically adjust unit distribution according to muscle strength, facial anatomy, and the level of softening desired.
Once diluted, the product is drawn into a sterile syringe and applied in small, precise points across the targeted facial muscles. The goal is to relax overactive areas while maintaining natural expression. Light, controlled technique is used to ensure the solution is delivered evenly for balanced, subtle results.
Post-treatment
Avoid touching, rubbing, or applying pressure to the treated areas for several hours.
Stay upright and avoid lying down for the next 3–4 hours.
Skip strenuous exercise, saunas, and heat exposure for the rest of the day.
Avoid alcohol shortly after treatment, as it may increase temporary redness or swelling.
Apply makeup only when the skin feels comfortable, using gentle, non-irritating products.
Mild redness or tiny marks may appear but typically fade quickly.
Initial smoothing effects usually begin within 2–5 days, with results continuing to improve.
Course of Treatments
How quickly will the result appear?
Before & Afters
What's Inside
- Dysport 500 Units Vial
One vial containing 500 units of Clostridium botulinum toxin type A in a fine, freeze-dried powder form. - Instruction Leaflet
Includes manufacturer guidelines on reconstitution, storage, and professional handling.
FAQ
Dysport 500 is used in cosmetic treatments to soften expression lines such as forehead lines, frown lines, and crow’s feet by relaxing targeted facial muscles.
Most people enjoy smoother-looking skin for about 3 to 6 months, depending on muscle strength and the area treated.
Early improvements often appear within 2 to 5 days, with full results showing around 10 to 14 days.
Dysport comes as a very fine freeze-dried powder that can look invisible in the vial. This is normal and all units are present.
It must be reconstituted only with preservative-free 0.9% sterile saline before use.
Yes. The 500-unit vial is suitable for treating several facial areas in one session when handled by trained professionals.
Most individuals get maintenance treatments 2 to 4 times per year to maintain consistent results.
Dysport 500 is available through our wholesale program for qualified aesthetic and medical practices. This French-manufactured botulinum toxin is produced to high purity standards and shipped with proper documentation to ensure authenticity. The 500-unit format is ideal for practices that treat multiple facial areas or require larger-volume vials for their cosmetic protocols. Our wholesale program maintains cold-chain handling and provides clear storage guidelines to preserve product quality. To review wholesale requirements and begin the qualification process, please complete our Wholesale Application.
How to properly store
- Unopened vials of Dysport 500 should be kept in a refrigerator at 2–8°C (36–46°F) and protected from light.
- The product must remain refrigerated until it is ready for reconstitution.
- After mixing with preservative-free saline, the reconstituted solution should also be stored at 2–8°C and used within 24 hours. Do not freeze the product after reconstitution.
- Always keep Dysport in its original packaging to maintain stability and ensure proper identification during handling.
Dysport 500 is intended for use by licensed medical professionals only. Improper storage or handling may affect product quality. We are not responsible for outcomes resulting from misuse, improper administration, or storage outside the recommended conditions.
Product Benefits Slims masseters and gets rid of forehead wrinkles
Age 28
The product came in about a week after I paid for the order and I am very impressed. The instructions for reconstitution are easy to follow and the package comes with 50 cc syringes and 0.9% NaCl solution as well. I will be ordering again when my current units wear off.
Product Benefits 2-Month Full-Face Review (It Works!)
Age 42
I waited two months for the Dysport to fully settle. I treated the whole face, and the results are balanced and fantastic.
Glabellar: RBF — Resting face is totally relaxed.
Forehead Lines: Super softened, but I can still move my brows. Not frozen!
Crow’s Feet: Way smoother when smiling, giving my eyes a youthful lift.
Eyebrow Lift: Got a subtle lift on the outer tail. Looks more awake.
Chin: The “orange peel” texture is completely vanished. Smooth chin all the time.
Lip Flip: Rolled the upper lip out for a fuller look (no filler!). It’s awesome, but took a few weeks to get used to—drinking from a straw or even eating was a little weird.
Final Verdict:
10/10 Highly Recommend. Everything is settled and looks refreshed. I hope this helps anyone looking in to it.
Amazing product