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Disclaimer: Products on our website are intended for use by qualified healthcare professionals only.

We are not responsible for any adverse effects from self-administration or for compensation of wasted or misused products.

The information on this page is not a substitute for professional medical advice, diagnosis or treatment. Always consult a professional healthcare provider for a personalized medical guidance.

Main Benefits

Swift correction of unsatisfactory results

Quickly dissolves HA-based fillers in cases of overfilling, uneven distribution, or incorrect placement.

Immediate and visible results

Effects appear within 24–48 hours.

Safe and reliable

Approved by the KFDA and developed in a GMP-certified facility.

Boosts fat-dissolving treatments

Enhances the effectiveness of lipodissolve injections.

Enhances drug absorption

Improves dispersion and absorption of other injected solutions.

Proven enzymatic activity

Effectively breaks down hyaluronic acid without damaging the body’s natural HA.

Liporase is a specialized injectable enzyme designed to safely and effectively dissolve hyaluronic acid fillers. It works by breaking down HA molecules at the injection site, helping to correct overfilling, misplaced fillers, or uneven results. In addition to its role as a reversal agent, Liporase can also enhance the effects of fat-dissolving treatments and improve absorption of other injectable solutions.

Indications

Liporase is recommended in the following situations:

Correcting excess or misplaced hyaluronic acid fillers.

Smoothing uneven results after filler injections.

Addressing accidental filler injection into a blood vessel.

Softening lumps, nodules, or granulomas caused by fillers.

Enhancing the effects of fat-dissolving treatments.

Targeting stubborn cellulite and localized fat deposits.

Active Ingredients

Hyaluronidase 1500 IU

The key enzyme that breaks down hyaluronic acid, allowing for the safe dissolution of fillers and enhanced absorption of other injectable solutions.

Lactose Hydrate 13.3 mg

A stabilizing agent that supports the formulation and activity of hyaluronidase.

Purity and Safety

Liporase is developed in a GMP-certified facility and classified as a Class III Medical Device, ensuring high standards of safety and manufacturing quality. It is approved by the KFDA as a reliable dissolution agent and has been clinically tested for both efficacy and safety.

Before treatment, a patch test is recommended to check for potential allergic reactions. Mild redness or swelling at the injection site is normal, but treatment should not proceed if hives or signs of anaphylaxis appear. These precautions help ensure patient safety while achieving effective results.

Mechanism of Action

Liporase contains hyaluronidase, an enzyme that works by breaking down hyaluronic acid (HA) molecules into smaller fragments. This accelerates the body’s natural ability to absorb and eliminate HA, allowing for the safe and effective dissolution of dermal fillers.

Because Liporase only targets synthetic HA from fillers, it does not damage the body’s own natural hyaluronic acid. In addition to correcting filler treatments, Liporase enhances the dispersion and absorption of other injected solutions, making it a valuable tool for boosting the effects of fat-dissolving treatments and improving the delivery of subcutaneous fluids.

What Makes Liporaise Different?

Liporase stands out as a trusted choice in aesthetic medicine thanks to its high enzymatic activity and proven safety profile. Manufactured in a GMP-certified facility and approved by the KFDA, it provides reassurance of both quality and reliability. Unlike other agents, Liporase is designed to act swiftly and precisely, dissolving unwanted or misplaced hyaluronic acid fillers without harming the body’s natural HA.

In addition to its role as a reversal agent, Liporase also offers unique versatility by enhancing fat-dissolving treatments and improving the absorption of injected solutions. This combination of safety, effectiveness, and multi-purpose use makes Liporase a distinct and valuable product for both practitioners and patients.

Treatment Areas

Liporase can be applied to different areas of the body where fillers or localized fat deposits require correction:

  • Face – for dissolving misplaced or excess fillers in the lips, cheeks, chin, or under-eye area.

  • Neck and jawline – to correct filler irregularities and support contouring treatments.

  • Arms and thighs – to enhance the effects of fat-dissolving procedures and address stubborn cellulite.

  • Abdomen and waistline – to assist in reducing localized fat and improving body contour.

Preparations Before Use

  • Dilution: Before use, dilute 3–4 ml of 0.9% NaCl solution (Saline) with one vial of Liporase powder.

  • Patch test: Always perform a skin test before injection to check for possible allergic reactions.

  • Mixing: Gently swirl the vial to dissolve the powder completely — do not shake vigorously.

  • Sterile technique: Ensure all instruments, syringes, and saline solutions are sterile prior to preparation and injection.

Dosage and Technique of Application

For filler dissolution:

Dilute one vial of Liporase with 3–4 ml of 0.9% NaCl solution (Saline). Inject the solution subcutaneously into the area where the hyaluronic acid filler needs to be removed. Results are typically visible within 24–48 hours. A follow-up filler procedure should only be performed after 10 days to allow the tissue to stabilize.

For fat-dissolving enhancement:

Dilute one vial of Liporase with 5 ml of 0.9% NaCl solution (Saline). Inject the solution into the area where fat-dissolving treatment will be performed, followed by the administration of the fat-dissolving agent. For best results, the two solutions should be injected separately.

Technique:

Liporase is applied using subcutaneous injections with sterile syringes. Injection depth and technique may vary depending on the treatment area and the extent of correction required.

What to Do After Injection Sessions?

  • Avoid re-injection of fillers in the treated area for at least 10 days.
  • Expect mild redness, swelling, or tenderness at the injection site — these usually subside within a few days.
  • Do not massage, rub, or apply pressure to the treated area unless instructed by a professional.
  • Avoid excessive heat exposure (sunbathing, saunas, hot tubs) for 24–48 hours.
  • Refrain from intense exercise or alcohol consumption for 24 hours after treatment to minimize swelling.
  • Contact a healthcare provider immediately if hives, difficulty breathing, or other allergic reactions occur.

Course of Treatments

1

Session

Filler correction usually requires a single session.

10–14

Days

If further sessions are necessary, they should be spaced at least 10–14 days apart to allow tissues to fully respond.

How quickly will the result appear?

Immediately

When used for filler correction, results are typically noticeable within 24–48 hours as the hyaluronic acid begins to break down and absorb. For fat-dissolving enhancement, visible improvements may take a little longer, often becoming more noticeable after a few sessions as the body naturally processes the dissolved fat.

 

Final, refined results can be assessed after 1–2 weeks, once any temporary swelling or redness has subsided.

Before and After

What's Inside

Each box of Liporase includes:

  • 10 vials of Liporase powder

  • Each vial contains 1500 IU of hyaluronidase with 13.3 mg of lactose hydrate

  • Vial size: 5 ml

FAQ

Liporase is an injectable enzyme that helps dissolve hyaluronic acid fillers. It is used to correct overfilling, misplaced injections, or uneven results. It can also be combined with fat-dissolving treatments to improve their effectiveness.

Most patients notice results within 24–48 hours after treatment. Final results are visible in about 1–2 weeks, once swelling has gone down.

Yes. Liporase is manufactured in a GMP-certified facility, approved by the KFDA, and has been clinically tested for safety and effectiveness. A patch test is always recommended before treatment to avoid allergic reactions.

No. Liporase only targets synthetic hyaluronic acid found in fillers. It does not harm the body’s naturally occurring HA.

Patients with a known allergy to hyaluronidase or lactose, or those who have experienced severe allergic reactions in the past, should not use this product. Always consult with a qualified medical professional before treatment.

It is recommended to wait at least 10 days after Liporase treatment before applying new filler, to allow the tissue to recover fully.

Yes, Liporase is available through our wholesale program. This hyaluronidase enzyme dissolves hyaluronic acid fillers for corrections and complications. Wholesale pricing helps clinics keep this essential reversal agent in stock. Complete our Wholesale Application.

How to Store

  • Store in a cool, dry place away from direct sunlight.

  • Keep at a temperature of 2°C – 25°C.

  • Do not freeze.

  • Keep vials in their original packaging until ready to use.

  • Ensure the product is kept out of reach of children.

This product is intended for use by licensed medical professionals only. We accept no responsibility for adverse effects or complications resulting from improper handling, self-administration, or use by unqualified individuals. No compensation will be provided for products that are damaged, wasted, or misused.

Customer Reviews

40 reviews for Liporase

5.0
Based on 40 reviews
5 star
97
97%
4 star
2
2%
3 star
0%
2 star
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1 star
0%

Customer Images

Image #1 from Anonymous
Image #1 from Anonymous

Anonymous

A must for any dermal filler procedures.

Image #1 from Anonymous
1-5 of 40 reviews

  1. Product Benefits Its good to have this on hand!

    Age 43


    any person that’s doing their own filler needs to have this on hand. Just in case!!


  2. Product Benefits Safety net!

    Age 62


    Liporase is a product that I believe any beauty DIY-er should always have on hand at any given time! The fact that Meamo shop offers great discounts on products and keeps prices low means that customers have a higher likelihood of being able to afford keeping such a product at the ready.


  3. Product Benefits Dissolve Filler

    Age 42


    Will always keep some of this on hand.

  4. Luckily did not need to use yet 🙂 But very important to have at hand.


  5. Product Benefits Dissolve filler

    Age 44


    This stuff is a good insurance policy to have on hand whenever you’re doing filler. And it works!

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