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August 21, 2024
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What Serum to Use with Microneedling? Types & Top 5 Recommendations
Choosing the right serum for microneedling can dramatically impact your results. The right serum penetrates deeply through micro channels created during treatment, delivering active ingredients directly into your skin for maximum effectiveness.
Micro needling creates controlled micro-injuries that open temporary pathways in your skin, allowing the best serums to be absorbed up to 300% more effectively than topical application alone. This enhanced penetration makes serum selection one of the most critical decisions in your micro needling treatment protocol.
At MeamoShop, we source authentic Korean skincare innovations, including serums, directly from Seoul manufacturers, ensuring you receive genuine products at wholesale pricing without middleman markup.
Key Takeaways
- Choose collagen-stimulating serums with PLLA or PDRN to stimulate collagen production and improve skin texture over time
- Focus on healing ingredients like hyaluronic acid, growth factor peptides, and vitamin C to support wound healing and skin repair
- Avoid harsh chemicals, including retinol, glycolic acid, and essential oils, immediately after treatment to prevent skin irritation
- Apply serums immediately during micro needling sessions when micro channels are open to penetrate deeply into skin layers
- Select based on skin types - hydrating serums for dry skin, collagen boosters for aging skin, brightening serums for uneven skin tone
- Follow proper aftercare by keeping your skin moisturized and protected from sun exposure for optimal results
Table of Contents
Understanding Serum Ingredients for Microneedling
Key Ingredients to Look For
Hyaluronic Acid
- Hydrates and plumps the skin by attracting up to 1,000 times its weight in water
- Creates deep moisture that keeps your skin moisturized throughout the healing process
- Works at multiple molecular weights to penetrate different skin layers
- Essential for dry skin and improving overall skin texture
Growth Factors
- Stimulate collagen production and accelerate cellular regeneration
- Signal your skin's healing abilities to repair controlled micro-injuries
- Support wound healing and reduce downtime after microneedling treatment
- Enhance production of collagen and elastin for long-term anti-aging benefits
Peptides
- Enhance skin elasticity and firmness by providing building blocks for collagen synthesis
- Work synergistically with microneedling to reduce fine lines and wrinkles
- Support the skin's natural healing response and promote healthy cells
- Particularly effective for aging skin and improving overall skin tone
Vitamin C
- Brightens and protects the skin from free radicals and environmental stressors
- Helps even out uneven skin tone and address hyperpigmentation
- Boosts collagen formation when applied after the initial healing period
- Creates radiant skin and supports long-term complexion improvements
Ceramides
- Strengthen the skin barrier and improve moisture retention
- Help repair damaged skin and protect against future irritation
- Particularly beneficial for sensitive skin types during the healing process
- Support your skin's ability to stay hydrated between microneedling sessions
PDRN (Polydeoxyribonucleotide)
- Derived from salmon DNA, clinically proven to accelerate wound healing
- Promotes tissue regeneration and reduces inflammation
- Exceptional for treating acne scars and improving uneven texture
- Enhances cellular activity and supports production of collagen
PLLA (Poly-L-Lactic Acid)
- Stimulates long-term collagen and elastin production for lasting results
- Creates gradual, natural-looking improvements over multiple microneedling treatments
- Addresses fine lines, wrinkles, and loss of skin elasticity
- Results can last 12-24 months with proper treatment protocol
Exosomes
- Deliver signaling molecules that communicate directly with healthy cells
- Accelerate skin repair and stimulate collagen synthesis at a cellular level
- Reduce downtime and enhance the overall benefits of microneedling
- Represent cutting-edge Korean skincare innovation for optimal results
Disclaimer: Individual results may vary. Always consult with a qualified professional for optimal results.
Choosing Serums by Purpose
Anti-Aging
- Serums containing hyaluronic acid combined with growth factors address fine lines and improve skin elasticity
- PLLA or PCL-based formulations stimulate ongoing production of collagen for long-term wrinkle reduction
- Peptide complexes enhance firmness and create a youthful complexion
- Exosome technology accelerates cellular regeneration for comprehensive anti-aging benefits
Hydration
- Hyaluronic acid serum provides immediate and deep hydration for dry skin
- Ceramide-enriched formulations strengthen your skin barrier and improve moisture retention
- Multi-molecular weight hyaluronic acid penetrates different layers for comprehensive hydration
- Essential for maintaining skin's healing during the microneedling procedure recovery
Brightening
- Vitamin C serums even out skin tone and reduce dark spots
- Glutathione acts as a powerful antioxidant and tyrosinase inhibitor for brightening effects
- Niacinamide helps improve overall complexion and reduce hyperpigmentation
- Best applied after initial healing phase (48-72 hours post-treatment)
Wound Healing
- PDRN accelerates your skin's natural healing response and reduces inflammation
- Growth factor serums support rapid tissue repair after controlled micro-injuries
- Exosome-based formulations enhance cellular communication for faster recovery
- Peptide complexes provide the building blocks needed for effective skin repair
Other Important Considerations
Fragrance-Free Formulations Avoid serums with fragrances, as they can cause skin irritation through open microchannels. Fragrance-free options reduce the risk of sensitivity and support a smooth healing process, especially important for sensitive skin types.
Non-Comedogenic Properties Choose serums labeled as non-comedogenic to prevent breakouts and clogged pores. This is particularly crucial after micro needling, when your skin is more vulnerable, and microchannels could potentially trap pore-blocking ingredients.
What Are the Benefits of Using Serums with Microneedling?
Enhanced Penetration and Absorption
Micro needling dramatically increases how deeply serum ingredients can penetrate into your skin. The microchannels created by tiny needles allow active ingredients to bypass the skin barrier and reach the dermis layer, where they stimulate collagen and elastin production most effectively.
Studies show that serums applied during or immediately after micro needling treatments absorb up to 300% better than topical application alone. This enhanced delivery means you get more value from every drop of serum, whether it's hyaluronic acid, growth factors, or vitamin formulations.
Accelerated Collagen Production
The combination of controlled micro-injuries from micro-needling and collagen-stimulating serums creates a synergistic effect. Your skin's natural healing response triggers production of collagen and elastin, while serum ingredients like PLLA, PDRN, or peptides provide the building blocks and signals needed to maximize collagen synthesis.
This dual approach leads to significant improvements in fine lines and wrinkles, skin texture, and overall skin elasticity. Over multiple microneedling sessions, cumulative collagen and elastin production reshape your skin from within for lasting anti-aging benefits.
Disclaimer: Individual results may vary. Always consult with a qualified professional for optimal results.
Targeted Treatment for Specific Concerns
Different best serums to use address different skin concerns when combined with micro needling treatment:
For acne scars: Growth factor serums and exosome-based formulations accelerate skin repair and help smooth uneven texture and damaged skin
For fine lines and wrinkles: Collagen-stimulating serums with PLLA or PCL reduce fine lines while improving skin elasticity for a youthful complexion
For uneven skin tone: Vitamin C serums and glutathione-containing formulations brighten and even out skin tone when applied during micro needling
For dry skin: Hyaluronic acid serum provides deep hydration, improving hydration levels and keeping your skin moisturized
For aging skin: Combination serums with growth factors, peptides, and collagen stimulators address multiple signs of aging simultaneously
Improved Wound Healing
High-quality microneedling serums contain ingredients that support your skin's healing process. PDRN, for example, is derived from salmon DNA and has been clinically proven to accelerate wound healing, reduce inflammation, and promote healthy cell regeneration.
When you apply these healing serums immediately after creating controlled micro-injuries, you're giving your skin exactly what it needs to recover faster and achieve better results. This means less downtime, reduced risk of skin irritation, and faster visible improvements.
Long-Lasting Results
Unlike topical application alone, serums used with microneedling create lasting changes in your skin's structure. Stimulation of collagen production continues for weeks after each treatment, as new collagen and elastin fibers form.
With proper microneedling sessions scheduled 4-6 weeks apart and appropriate serum selection, you can achieve optimal results that compound over time. Each treatment builds on the previous one, progressively improving skin texture, reducing wrinkles, and creating radiant skin.
Disclaimer: Individual results may vary. Always consult with a qualified professional for optimal results.
Enhanced Skin Barrier Function
While microneedling temporarily compromises your skin barrier, using the right serums can help strengthen it over time. Ingredients like hyaluronic acid, ceramides, and growth factors support your skin's natural barrier function, improving your skin's ability to retain moisture and protect against environmental damage.
This leads to a healthy skin appearance, better resilience, and reduced sensitivity in the long term.
How Do You Pick the Right Serum for Microneedling?
Consider Your Primary Skin Concerns
Start by identifying what you want to improve. Different serums excel at addressing specific concerns:
Aging skin with fine lines: Choose collagen-stimulating serums containing PLLA, PCL, or growth factor complexes
Acne scars and uneven texture: Select exosome-based or PDRN serums that accelerate skin repair and smooth texture
Dry skin needing hydration: Opt for hyaluronic acid serum with multiple molecular weights for deep moisture
Uneven skin tone and dark spots: Pick serums with vitamin C, glutathione, or niacinamide (like ordinary niacinamide 10 zinc)
Multiple concerns: Consider combination serums like PLLA Cube PiNk VOL that address aging, texture, and brightness
Evaluate Your Skin Types
Your specific skin type influences which serums will work best after micro needling:
Sensitive skin: Choose gentle formulations without harsh chemicals, fragrances, or high concentrations of active ingredients. Start with pure hyaluronic acid serum before progressing to more potent options.
Oily or acne-prone skin: Select lightweight serums that won't clog pores. Avoid heavy oils and look for non-comedogenic formulations.
Dry skin: Prioritize deep hydration with hyaluronic acid-rich formulas. Consider serums that contain moisturizing ingredients alongside collagen stimulators.
Mature or aging skin: Focus on serums that support maximum collagen and elastin production, such as PLLA, PCL, or growth factor cocktails.
Assess Ingredient Quality and Concentration
Not all microneedling serums are created equal. Look for:
Clinical-grade ingredients: Professional microneedling serums from reputable Korean manufacturers typically offer higher quality and potency
Appropriate concentrations: Higher concentrations (like 23% PCL in Rejuner Black or 3% PDRN in Jeunetique EXO) deliver stronger results but may cost more
Serum ingredients synergy: The best serums combine complementary active ingredients that work together (e.g., PLLA + hyaluronic acid + vitamin C)
Sterility and packaging: For use after microneedling, serums must be sterile to prevent infection through open microchannels
Factor in Treatment Depth and Frequency
Shallow microneedling treatments (0.25-0.5mm): Can work with lighter serums like pure hyaluronic acid or vitamin formulations applied at home with a derma roller
Medium depth (0.5-1.5mm): Best paired with growth factor serums or moderate collagen stimulators during a professional microneedling procedure
Deep microneedling (1.5-2.5mm): Requires professional-grade serums like PLLA or PCL formulations administered by a skincare professional
Frequent sessions: If you're doing microneedling treatments monthly, choose gentler hydrating serums to avoid over-stimulation
Spaced sessions: With 6-8 weeks between microneedling sessions, you can use more powerful collagen-stimulating formulations for optimal results
Velash SHGF11
$89.40
Earn 4 Points
VELASH SHGF11 Scalp Advanced Clinic's specialized formulation offers a holistic approach to scalp health, hair growth promotion, and hair loss prevention, effectively nourishing the scalp, promoting healthy hair growth, and addressing a wide range of scalp-related concerns.
- Scalp Nourishment and Rejuvenation: Specialized scalp nutrition product formulated to nourish and rejuvenate the scalp, promoting healthy hair growth from the roots. Addresses the root causes of hair loss by providing essential nutrients to the scalp, contributing to improved hair strength and vitality.
- Hair Growth Promotion and Loss Prevention: Promotes hair growth and nourishes the scalp, working to prevent hair loss and supporting the maintenance of healthy hair follicles. Targets deficiencies in scalp health that can lead to dull, sparse, and brittle hair, actively addressing the issues to minimize hair loss.
- Versatile Effectiveness: Effective for various types of hair loss and scalp concerns, providing comprehensive support for scalp health and hair rejuvenation. Addresses conditions such as diffuse alopecia, dandruff, dry hair, and excessive sebum production, offering a versatile solution for diverse scalp and hair-related issues.
Rejuner Black
Price range: $95.50 through $349.50
Earn up to 17 Points
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Rejuner Black is a cutting-edge skin booster designed to stimulate collagen production and achieve deep skin rejuvenation, particularly for areas like the temples, neck, and under eyes.
- High Concentration of PCL: Contains 23% polycaprolactone, which boosts rejuvenation and delivers noticeable results.
- Long-Lasting Results: Effects can last up to 24 months, significantly improving skin elasticity and texture.
- Collagen Stimulation: Enhances neocollagenesis, effectively reducing deep wrinkles and tightening the skin.
Rejuner Gold
Price range: $95.50 through $349.50
Earn up to 17 Points
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This product has multiple variants. The options may be chosen on the product page
Rejuner Gold is a premium skin booster designed to enhance skin rejuvenation and hydration through advanced collagen stimulation.
- High Concentration of PCL: Contains 23% polycaprolactone, which boosts rejuvenation and delivers noticeable results.
- Long-Lasting Results: Effects can last up to 24 months, significantly improving skin elasticity and texture.
- Collagen Stimulation: Enhances neocollagenesis, effectively reducing deep wrinkles and tightening the skin.
Miracle Touch BR
Price range: $29.00 through $99.00
Earn up to 4 Points
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This product has multiple variants. The options may be chosen on the product page
Miracle Touch BR is a skin booster based on peptides, niacinamide and ascorbic acid (vitamins B3 and C). It is most effective against freckles and UV damage caused by the sun. Miracle Touch also contains XT80 Complex, which lightens the skin and reduces the severity of age spots and dyschromia.
- Effective Against Freckles and UV Damage: The Miracle Touch BR Booster, packed with peptides, niacinamide, and vitamins B3 and C, shields against UV damage and aids in fading freckles and pigmentation resulting from sun exposure.
- Skin Lightening and Spot Reduction: Infused with the XT80 Complex, this booster lightens skin, diminishes age spots, and evens out skin tone, targeting pigmentation issues for a brighter complexion.
- Nourishing and Protective: Rich in vitamins and peptides, the Miracle Touch BR Booster not only treats skin concerns but also nourishes and safeguards the skin, promoting overall health and radiance.
Consider Your Budget and Treatment Goals
Professional collagen-stimulating serums like PLLA Cube or Rejuner Black cost more but deliver longer-lasting benefits (12-24 months). Basic hyaluronic acid serum options are more affordable but require more frequent use after microneedling for maintenance.
Calculate the cost per treatment session and factor in how many microneedling treatments you'll need. Sometimes investing in premium serums upfront saves money long-term by reducing the total number of sessions required for your desired results.
Consult with a Skincare Professional
Before your first micro needling procedure, discuss serum options with a qualified practitioner. They can:
- Assess your specific skin condition and skin types
- Recommend appropriate serum ingredients for your goals
- Explain proper application timing and technique
- Monitor your skin's healing and adjust serum selection between microneedling sessions
- Help you avoid products that could cause skin irritation or complications
Professional guidance ensures you select serums that complement your micro needling treatment rather than compromising results or safety.
Research Brand Reputation and Reviews
Look for microneedling serums from established Korean skincare manufacturers with strong safety records. Read reviews from other users who have similar skin concerns and skin types. Pay attention to feedback about:
- Effectiveness at improving skin texture, reducing wrinkles, or addressing specific concerns
- Any reported skin irritation or side effects
- How quickly results appeared after microneedling treatments
- Whether results lasted through multiple microneedling sessions
Products from MeamoShop, sourced directly from Seoul, offer authentic Korean innovations with temperature-controlled shipping to maintain serum effectiveness.
Caratfill Skin Booster
Price range: $18.20 through $128.70
Earn up to 6 Points
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This product has multiple variants. The options may be chosen on the product page
Caratfill Skinbooster offers a comprehensive skincare solution by addressing hydration, wrinkle reduction, skin firmness, and tone improvement. Its rich composition of essential nutrients and regenerators makes it a valuable addition to skincare routines aiming for healthy, radiant skin.
- Anti-Aging & Cellulite Reduction: Caratfill Skinbooster not only offers anti-aging benefits but also shows promising results in mesotherapy for cellulite treatment. The blend of nutrients and regenerators in Caratfill works synergistically to address various skin concerns comprehensively.
- Skin Hydration & Wrinkle Reduction: Caratfill Skinbooster provides effective hydration to the skin, aiding in reducing wrinkles and fine lines. The presence of hydrolyzed glycosaminoglycans works to moisturize the skin, improving its texture and overall appearance.
- Enhanced Skin Texture & Turgidity: This mesotherapy "cocktail" helps in improving skin texture and turgidity, promoting a smoother and firmer complexion. It works by replenishing essential nutrients that support collagen and elastin production for skin firmness.
- Skin Tone Improvement & Acne Reduction: Caratfill Skinbooster contributes to enhancing skin tone and reducing acne breakouts. By supplying nutrients that support skin health, it helps in achieving a more even skin tone and reducing acne occurrence.
Ami Eyes PDRN 2ml
$39.70
Earn 1 Point
Designed specifically for needle mesotherapy, AMI EYES targets the eye area and tear troughs, providing a filling effect without the risk of lumps or lymphatic stagnation. This innovative formula encourages skin to produce more collagen and elastin, markedly enhancing the dermis's structure and appearance. Additionally, AMI EYES aids in internal skin regeneration, promoting overall skin health and vitality.
- Collagen Stimulation: Enhances the production of collagen, thereby improving the structure and appearance of the skin.
- Dark Circle Reduction: Effective in combating dark circles under the eyes, promoting a more rejuvenated and refreshed appearance.
- Facial Rejuvenation: Helps in providing overall rejuvenation for the delicate skin around the eyes, contributing to a revitalized look.
Dermaheal SB
$119.50
Earn 5 Points
Dermaheal SB is a mesotherapy solution designed specifically for skin brightening and pigmentation reduction. It contains a blend of growth factors, peptides, and vitamins that target skin tone irregularities.
- Brightening Effect: Helps lighten hyperpigmentation and dark spots for a more even skin tone.
- Skin Rejuvenation: Promotes overall skin health and radiance by enhancing cell renewal.
- Moisturizing Properties: Provides hydration, improving skin texture and smoothness.
REVS PRO 32
$99.50
Earn 4 Points
REVS PRO 32 is an innovative skin rejuvenation product that leverages the combined power of high and low molecular weight Hyaluronic Acid to deliver unmatched moisturization and skin elasticity. Specially designed to restore your skin's youthful radiance, REVS PRO32 promises not only to hydrate and lift but also to balance and regenerate skin for a luminous, youthful complexion.
One syringe is sufficient for a single procedure covering the face area. Results last from 6 to 9 months depending on individual skin type, age, and lifestyle.
- Deep Skin Hydration: REVS PRO 32 skin booster provides deep hydration to the skin, helping to alleviate dryness and improve overall moisture levels. It works to replenish and retain moisture, contributing to a plumper, more hydrated, and youthful-looking complexion.
- Enhanced Skin Firmness: This skin booster contains ingredients that promote skin firmness and elasticity, leading to a more lifted and toned appearance. It helps to address signs of aging such as fine lines and wrinkles, supporting a firmer and more resilient skin texture.
- Improved Skin Radiance: The REVS PRO 32 contributes to improving skin radiance and luminosity, enhancing the natural glow of the skin. It aids in revitalizing the complexion, promoting a healthier and more radiant overall appearance.
Top 5 Recommended Serums for Microneedling
Key ingredients:
- Exosomes (1.3 billion per mL)
- 3% PDRN (Polydeoxyribonucleotide)
- 7% Sodium Hyaluronate (Hyaluronic Acid)
- Atelocollagen
- Cellular Growth Factors
- Ultra-short Peptides
What makes it stand out:
- Best serums for accelerating the healing process and reducing downtime after a microneedling procedure
- Exosome technology delivers signaling molecules that penetrate deeply to stimulate collagen and elastin production
- Exceptional for treating acne scars, reducing fine lines, improving uneven skin tone, and repairing damaged skin
- Growth factor complex supports skin's healing and cellular regeneration for radiant skin
- Works quickly - many users see brighter, glowing skin within one week of microneedling sessions
- Rated 4.91/5 by customers specifically for use after microneedling treatment
2. Curenex
Key ingredients:
- PDRN (Salmon DNA/Polydeoxyribonucleotide)
- 15 Multi-Peptide Complex (including EGF, BFGF, VEGF, TGF-β, KGF)
- Hyaluronic Acid (non-crosslinked)
- Glutathione
- Hydrolyzed Collagen
- Multiple specialized peptides (Palmitoyl Tripeptide-5, Copper Tripeptide-1, Acetyl Hexapeptide-8, and others)
What makes it stand out:
- Advanced PDRN technology accelerates the skin's natural healing and promotes tissue regeneration
- 15-peptide complex works synergistically to promote anti-aging benefits, collagen formation, and melanin inhibition
- Exceptional for treating dryness, dullness, loss of elasticity, fine lines, acne scars, and uneven skin tone
- Glutathione acts as a powerful antioxidant and tyrosinase inhibitor, helping to brighten the complexion and eliminate free radicals
- Works with mesotherapy, dermal rollers, micro-needling devices, or manual injections
- Many users report an immediate glow with continued improvements over 1-2 weeks
Key ingredients:
- Poly-L-Lactic Acid (PLLA) - 100mg
- PDRN (Polydeoxyribonucleotide)
- Vitamin C
- Glutathione
- Sodium Hyaluronate (Hyaluronic Acid)
What makes it stand out:
- Stimulates long-term production of collagen for improved skin elasticity and youthful complexion
- INCUBE™ technology protects active ingredients and ensures sustained delivery for optimal results
- Combines multiple benefits: collagen synthesis, hydration, brightening, and antioxidant protection
- Works on fine lines and wrinkles, uneven texture, and damaged skin from sun exposure
- Provides both immediate hydration and long-term collagen stimulation over treatment sessions
- Suitable for all skin types, including sensitive skin and aging skin
Key ingredients:
- High-purity Type 1 Atelocollagen (porcine-derived)
- Cold-processed collagen maintaining natural triple-helix structure
What makes it stand out:
- Direct collagen supplementation for areas with significant collagen deficiency and aging skin
- Cold-processing method preserves natural collagen structure for better absorption and effectiveness during wound healing
- Type 1 atelocollagen reduces immune reactions and skin irritation compared to regular collagen
- Excellent for improving skin texture, skin elasticity, and treating fine lines and wrinkles
- Works on multiple areas: face, neck, décolletage, and hands for comprehensive treatment
- FDA-approved Class 4 medical device with a high safety profile for all skin types
- Supports rapid tissue repair and helps skin recover quickly after a microneedling procedure
- Combines well with other active ingredients in your skincare routine
Key ingredients:
- PLA (Poly-L-Lactic Acid) Microspheres - 200mg
- SCMC (Sodium Carboxymethyl Cellulose)
- Smart SPDS™ Technology for uniform particle delivery
What makes it stand out:
- Dual-action formula: immediate smoothing effect plus long-term collagen and elastin production
- SCMC provides instant hydration and reduces post-treatment side effects for healthy cells
- Results last up to 24 months - the longest-lasting benefits among the best serums to use with micro needling
- Smart SPDS™ ensures perfectly uniform microspheres for consistent treatment and reduces wrinkles
- Stimulates natural collagen synthesis for gradual, natural-looking improvements in skin tone
- Biodegradable and biocompatible - safely absorbed by the body over time during the healing process
PLLA Cube PiNk VOL.
$120.00
Earn 6 Points
A next-generation collagen-stimulating skin booster that combines powerful actives with advanced delivery technology for visible rejuvenation.
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Formulated with PLLA, PDRN, Vitamin C, Glutathione, and Sodium Hyaluronate to firm and regenerate skin
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Uses INCUBE™ tech for uniform PLLA particle delivery and gentle exfoliation
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Instantly hydrates and restores radiance in just one minute
Jeunetique EXO
Price range: $38.40 through $151.20
Earn up to 7 Points
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This product has multiple variants. The options may be chosen on the product page
Download Brochure
An innovative skinbooster based on the rejuvenating action of exosomes at the subcellular level. The action of Meamo Jeunetique Exo is based on the introduction of active signaling molecules into the dermis using exosomes. The anti-aging properties of Meamo Jeunetique Exo are enhanced by the inclusion of polydesoxyribonucleotide (PDRN), atelocollagen, cellular growth factors and ultra-short peptides.
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Exosomes Enhance cellular communication, accelerating skin repair and reducing inflammation. |
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PDRN Drives deep cellular regeneration, renewing and revitalizing your complexion. |
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Collagen & Peptides Boost elasticity and hydration, smoothing fine lines and restoring firmness. |
CollareJu collagen stimulator
$95.00
Earn 4 Points
COLLAREJU is a high-purity Type 1 collagen supplement derived from porcine sources, designed for direct injection into areas with collagen deficiency. It uses a unique cold-processing method to preserve the collagen’s natural structure and reduce immune reactions, offering effective tissue repair and rejuvenation.
- Fast Collagen Absorption: Promotes rapid tissue repair and rejuvenation.
- Cold-Processed: Maintains collagen's natural structure for maximum effectiveness.
- Reduced Immune Risk: Uses Type 1 atelocollagen to minimize immune reactions.
BEAUY Collagen Stimulator (PLLA)
Original price was: $139.00.$111.00Current price is: $111.00.
Earn 5 Points
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BEAUY is a next-generation powder-type collagen stimulator made with PLA and SCMC, designed to stimulate natural collagen production for long-lasting volume and skin rejuvenation. With its biodegradable microspheres and smooth injection properties, BEAUY offers a safe, effective alternative to traditional fillers—delivering results that can last up to 24 months.
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Perfect spherical shape Uniform microspheres ensure smooth application, consistent performance, and natural results. |
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Ease of preparation Freeze-dried powder dissolves quickly, reducing prep time and streamlining treatments. |
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Biodegradable Components Made from PLA polymer that fully decomposes in the body through natural metabolism. |
How to Apply Serum After Microneedling
Prepare Your Skin
Before your microneedling treatment, cleanse your face thoroughly with a gentle cleanser. Your skin should be completely clean, free of makeup, oils, and skincare products. A skincare professional will typically disinfect the treatment area to create controlled micro-injuries safely. [1]
During the Microneedling Procedure
The best time to apply serums is during your microneedling session, when the microchannels are actively open. As the tiny needles create punctures, serum ingredients can penetrate deeply into the dermis layer. Most professionals apply serums directly during treatment to maximize absorption through the open micro channels.
Your practitioner will use a derma roller or an automated microneedling device to create controlled micro-injuries. The depth varies based on your specific skin concerns - shallow needling for fine lines, deeper for acne scars or wrinkles.
Immediate Post-Treatment Application
Immediately after microneedling, your skin is primed to absorb active ingredients. Apply hyaluronic acid serum or your chosen pure serum while the microchannels remain open (for the first 30-60 minutes). This timing ensures serum ingredients penetrate deeply for maximum benefits of microneedling.
Use clean hands or sterile applicators to gently pat—never rub—serum onto your skin. Microinjuries make your skin sensitive, so gentle application helps prevent additional irritation and supports wound healing.
First 24-48 Hours Post-Treatment
Keep your skin moisturized with healing serums containing hyaluronic acid, growth factors, or peptides. Avoid harsh chemicals, vitamin C (initially), retinol, and exfoliating products that could irritate the skin. Your skin's healing abilities are working overtime to repair controlled micro injuries and stimulate collagen production.
Avoid sun exposure and always wear SPF during the day. Your skin barrier is temporarily compromised, making you more vulnerable to damage from environmental stressors. [2]
Days 3-7: Continued Healing
Continue applying hydrating serums to keep your skin hydrated and support the healing process. You can gradually reintroduce gentle active ingredients if your skin shows no signs of sensitivity. Watch for any skin irritation and adjust your skincare routine accordingly.
During this phase, collagen synthesis begins ramping up. The micro channels have closed, but cellular activity beneath your skin surface intensifies as healthy cells multiply and collagen and elastin production increase.
Long-Term Serum Protocol
After initial healing, establish a consistent serum routine. Use growth factor serums, vitamin C (for brightening), or collagen-stimulating ingredients between your microneedling treatments. This supports the ongoing production of collagen and maintains optimal results from each treatment.
Most skincare professionals recommend microneedling sessions every 4-6 weeks. Between treatments, your daily serum use enhances the benefits and prepares your skin for the next microneedling procedure.
Disclaimer: Individual results may vary. Always consult with a qualified professional for optimal results.
Miracle X
Price range: $79.00 through $299.00
Earn up to 14 Points
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This product has multiple variants. The options may be chosen on the product page
An innovative next-generation aesthetic product containing polycaprolactone (PCL) and botulinum-like peptides. Miracle X stimulates natural collagen production, enhances skin firmness, and delivers a “liquid facelift” effect without surgery.
- 🌿 Comprehensive rejuvenation — improves skin tone and elasticity while smoothing texture.
- ⚡ Instant lifting effect — visible tightening and firmness after the first sessions.
- 💎 Long-lasting results — promotes skin renewal with effects lasting up to 6–12 months.
Ami Eyes PDRN 2ml
$39.70
Earn 1 Point
Designed specifically for needle mesotherapy, AMI EYES targets the eye area and tear troughs, providing a filling effect without the risk of lumps or lymphatic stagnation. This innovative formula encourages skin to produce more collagen and elastin, markedly enhancing the dermis's structure and appearance. Additionally, AMI EYES aids in internal skin regeneration, promoting overall skin health and vitality.
- Collagen Stimulation: Enhances the production of collagen, thereby improving the structure and appearance of the skin.
- Dark Circle Reduction: Effective in combating dark circles under the eyes, promoting a more rejuvenated and refreshed appearance.
- Facial Rejuvenation: Helps in providing overall rejuvenation for the delicate skin around the eyes, contributing to a revitalized look.
Jeunetique EXO
Price range: $38.40 through $151.20
Earn up to 7 Points
Select options
This product has multiple variants. The options may be chosen on the product page
Download Brochure
An innovative skinbooster based on the rejuvenating action of exosomes at the subcellular level. The action of Meamo Jeunetique Exo is based on the introduction of active signaling molecules into the dermis using exosomes. The anti-aging properties of Meamo Jeunetique Exo are enhanced by the inclusion of polydesoxyribonucleotide (PDRN), atelocollagen, cellular growth factors and ultra-short peptides.
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Exosomes Enhance cellular communication, accelerating skin repair and reducing inflammation. |
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PDRN Drives deep cellular regeneration, renewing and revitalizing your complexion. |
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Collagen & Peptides Boost elasticity and hydration, smoothing fine lines and restoring firmness. |
Touch Up
Price range: $39.00 through $149.00
Earn up to 7 Points
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This product has multiple variants. The options may be chosen on the product page
The Miracle Touch Up Skin Booster is a skincare product designed to provide a lifting effect and enhance skin firmness. It contains PCL as the active ingredient and is formulated to provide long-lasting results.
- Lifting Effect: The Miracle Touch Up Skin Booster, featuring PCL as the active ingredient, provides a visible lifting effect, enhancing skin firmness and elasticity for a more youthful appearance.
- Extended Results: Despite working more slowly than Miracle L, this booster offers long-lasting results, ensuring a sustained improvement in skin texture and tone over time.
- Enhanced Firmness: By incorporating PCL into its formulation, the Miracle Touch Up Skin Booster helps improve skin firmness and tightness, contributing to a smoother and more lifted look.
Frequently Asked Questions
Do you need to use a serum with microneedling?
Yes, serums are highly recommended with microneedling for optimal results. Serums applied during or immediately after treatment penetrate up to 300% deeper through open microchannels, delivering active ingredients directly into deeper layers where they can effectively boost results and accelerate healing.
Which serums should not be used with microneedling?
Avoid retinol, glycolic acid, benzoyl peroxide, essential oils, and high-concentration vitamin C immediately after treatment. These can cause severe irritation through open channels. Stick to gentle, healing ingredients like hyaluronic acid, growth factors, and PDRN for the first 48-72 hours.
What pairs well with microneedling?
Hyaluronic acid serums, growth factors, PDRN, collagen stimulators (PLLA/PCL), LED light therapy, and PRP all pair excellently with treatments. Always follow with gentle moisturizers, strict sun protection, and proper spacing (4-6 weeks) between sessions for best outcomes.
Final Thoughts
Selecting what serum to use with microneedling is one of the most important decisions for maximizing your microneedling treatment results. The best serums deliver active ingredients through microchannels into your skin's deeper layers, where they stimulate collagen production, improve skin texture, and create lasting improvements in your complexion.
Whether you're targeting fine lines and wrinkles, acne scars, uneven skin tone, or overall skin rejuvenation, the right combination of micro needling and high-quality serums from MeamoShop delivers transformative results that improve with each treatment session.
Ready to enhance your microneedling results? Explore our complete collection of professional-grade microneedling serums and devices sourced directly from Seoul. From innovative skin boosters featuring exosome technology to proven PLLA formulations, we offer everything you need for optimal results. Get started with 12.5% off using code MEAMOBLOG at checkout.
References:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11499218/
https://www.sciencedirect.com/topics/nursing-and-health-professions/sunscreen
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