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Main Benefits
Skin Regeneration
Stimulates cell renewal and tissue repair through high-concentration polynucleotides derived from premium salmon DNA.
Collagen & Elastin Boost
Enhances natural collagen and elastin synthesis for improved firmness, elasticity, and overall skin texture.
Deep Hydration
Delivers intense moisture to the skin, restoring smoothness and a healthy glow.
Refined Skin Texture
Minimizes pores and helps even out skin tone for a more youthful, radiant appearance.
Accelerated Healing
Promotes faster recovery and improved skin barrier function after procedures.
Comfortable Application
Formulated with lidocaine to minimize discomfort during mesotherapy or microinjection treatments.
Indications
Youthfill PN is indicated for individuals seeking:
Skin Rejuvenation
Improvement of dull, tired, or aging skin through enhanced regeneration and hydration.
Fine Line and Wrinkle Reduction
Treatment of early to moderate signs of aging, including fine lines and surface wrinkles.
Elasticity Restoration
Revitalization of sagging or lax skin, especially in areas showing loss of firmness.
Post-Procedure Recovery
Support for skin healing and regeneration following laser, peeling, or microneedling treatments.
Uneven Skin Texture
Smoothing of rough or coarse skin to restore softness and clarity.
Preventive Anti-Aging Care
Maintenance treatment for youthful, radiant, and resilient skin.
This minimally invasive treatment delivers long-lasting results, making it an effective solution for those seeking natural-looking facial rejuvenation.
Ingredients
Polynucleotide (25 mg/mL)
It enhances skin elasticity, hydration, and resilience while accelerating wound healing.
Lidocaine
A local anesthetic that provides pain relief during injection, ensuring a comfortable treatment experience.
Mechanism of Action
Youthfill PN works through cellular regeneration and collagen stimulation powered by high-concentration polynucleotides (PN) derived from premium salmon DNA.
Cellular Repair and Regeneration
Polynucleotides penetrate the dermal layer and activate fibroblast activity, encouraging the natural renewal of skin cells.
This enhances cell viability, supporting faster recovery of damaged or aging tissue.
Collagen and Elastin Production
By stimulating fibroblasts, PN boosts the synthesis of collagen and elastin fibers, restoring skin firmness and improving elasticity over time.
Hydration and Skin Barrier Support
PN molecules bind water efficiently, maintaining optimal hydration within the dermis and improving the skin’s protective barrier function.
Anti-Inflammatory and Wound-Healing Effects
Polynucleotides help reduce inflammation and accelerate micro-wound healing, leading to smoother, stronger, and more even skin.
Enhanced Comfort and Safety
The inclusion of lidocaine (3 mg/mL) ensures a comfortable application, minimizing pain or irritation during mesotherapy or injection sessions.
Product Preparation
Inspection Before Use
Check the expiration date and integrity of the syringe packaging. Do not use if the seal is broken or if the solution appears cloudy or discolored.
Storage Conditions
Keep stored in a cool, dry place between 1–30 °C.
Avoid direct sunlight, heating, or freezing the product, as this can affect its efficacy and safety.
Before Injection
Cleanse and disinfect the treatment area thoroughly.
Ensure aseptic handling of all equipment and materials.
The product is ready-to-use; no dilution or mixing is required.
Preparation for Application
Attach a sterile fine-gauge needle appropriate for mesotherapy or microinjection (typically 30–32 G).
Remove any air bubbles from the syringe before administration.
Treatment areas
Youthfill PN is suitable for delicate and aging areas that require hydration, elasticity, and overall rejuvenation. It can be applied to:
Full Face: Enhances skin tone, texture, and firmness for overall rejuvenation.
Periorbital Area (Around Eyes): Reduces fine lines, puffiness, and signs of fatigue.
Neck: Improves elasticity and smoothness of thin, crepey skin.
Décolletage: Restores hydration and firmness to the chest area.
Hands: Revitalizes thin or aging skin for a smoother, more youthful appearance.
Dosage and technique
Recommended Dosage
Full Face: Minimum of 2 mL per session for optimal rejuvenation.
- Each syringe contains 2.5 mL, suitable for one full-face treatment or smaller targeted areas.
Injection Depth
Administer Youthfill PN into the superficial dermis, approximately 1 mm deep.
- Avoid injecting too deeply to prevent uneven distribution or nodules.
Injection Techniques
Papule Technique: Small micro-injections spaced evenly (about 1 cm apart) across the treatment area for uniform absorption.
Nappage Technique: Multiple tiny injections in a linear or cross-hatched pattern for fine lines or delicate areas.
Point-by-Point Technique: Focused injections in specific problem zones such as crow’s feet or nasolabial folds.
Gently massage the treated area to ensure even distribution of the product.
Avoid applying makeup, intense exercise, or heat exposure (e.g., saunas, sunbathing) for 24 hours post-treatment.
Professional Use Only
- Must be administered by licensed medical professionals experienced in mesotherapy or skin booster procedures to ensure precision and safety.
Post-treatment
After receiving Youthfill PN, it’s normal to experience mild redness, swelling, or tiny papules at the injection sites — these usually resolve within 1–2 days. The treated area should be kept clean, and makeup or harsh skincare products should be avoided for at least 24–48 hours.
During this period, avoid direct sunlight, saunas, hot showers, and intense exercise, as heat and sweat can increase irritation. Keep the skin well-hydrated with gentle moisturizers and apply a high-SPF sunscreen daily to protect the newly rejuvenated skin. As collagen production and cellular repair continue, the skin gradually becomes firmer, smoother, and more radiant over the following weeks. For the best results, maintain consistent aftercare and complete the full treatment course as recommended.
Course of Treatments
How quickly will the result appear?
Before & Afters
What's Inside
1 Pre-filled Syringe × 2.5 mL
Each syringe contains Polynucleotide (25 mg/mL) and Lidocaine (3 mg/mL) for effective rejuvenation with minimal discomfort.Sterile Packaging
Each unit is individually sealed to maintain hygiene and product integrity until use.Ready-to-Use Formula
No dilution or mixing required — the syringe is pre-loaded and ready for direct application.
FAQ
Youthfill PN is a skin rejuvenation injectable formulated with high-concentration polynucleotides (PN) from salmon DNA. It helps improve skin texture, elasticity, and hydration by stimulating collagen and supporting cell repair.
It promotes skin regeneration, boosts collagen and elastin, delivers deep hydration, and enhances overall skin radiance. The added lidocaine ensures a more comfortable treatment.
Polynucleotides activate fibroblast cells, which boost collagen and tissue regeneration. This helps the skin repair itself naturally, leading to firmer, smoother, and more youthful-looking skin.
Youthfill PN can be used on the face, neck, décolletage, around the eyes, and hands — anywhere skin needs hydration, firmness, and renewal.
Minor redness or swelling may occur but typically subsides within 24–48 hours. Most people can resume daily activities the same day.
Avoid makeup, sun exposure, and intense exercise for 24–48 hours. Keep the skin moisturized and always apply SPF 30+ sunscreen to protect treated areas.
Yes, MeamoShop provides wholesale pricing on Youthfill PN for qualified buyers. This advanced Korean aesthetic injectable contains high-concentration polynucleotide (25mg/mL) with lidocaine in a generous 2.5mL syringe—promoting skin regeneration, improved texture, and restored elasticity through enhanced collagen production. Wholesale accounts help med spas stock this premium PN booster at competitive rates. Visit our wholesale application page to apply.
How to store
Store in a cool, dry place at a temperature between 1°C and 30°C.
Keep the product away from direct sunlight, heat, and moisture.
Do not freeze or heat the syringe, as temperature changes can damage the formulation.
Always check the expiration date before use and do not use if the packaging is damaged or opened.
Youthfill PN is a professional-grade injectable intended only for use by licensed medical professionals trained in aesthetic or dermatological procedures. Improper handling, storage, or self-administration may result in reduced product efficacy or potential adverse effects. We are not liable for misuse, self-injection, or unauthorized professional use, nor will we compensate for products that have been wasted or mishandled.
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Product Benefits de grands espoirs
Age 44
je mise beaucoup pour améliorer la zone des cernes, avec une seringue je fais les deux cernes et la lèvre blanche, sans ah donc les gonflements sont temporaires.
Product Benefits replumpe
Age 44
Utilisé au départ de manière trop rapprochés (15 jours), ne pas faire cette erreur mais laisser un mois entre deux traitements et ne rien faire entre, pas de peeling ou autre stimulation
Product Benefits bien
Age 44
J’aime son utilisation simple, avec de la lidocaïne dedans on ne sent rien du tout, livré avec deux aiguilles de 31g
Product Benefits des résultats prometteurs
Age 44
Je base beaucoup d’espoirs dans ce produit, les PN sont réputés améliorer les zones compliquée à traiter.
utilisé sur la zone des cernes et de la lèvre blanche, des gonflement pendant 3 jours, car le produit est un peu hydrophile, mais l’absence d’acide hyaluronique est un vrai avantage par rapport à d’autres produits pour ne pas rester gonflée des semaines entières
Product Benefits Smooth skin
Age 48
I’ve used this a couple of times now. Easy to use and smoother skin right off the bat