Medicube PDRN Pink Collagen Exosome Shot Serum 2,000 PPM

$19.50

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It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

Medicube PDRN Pink Collagen Exosome Shot 2000 is a powerful skin-booster serum that delivers 99 % salmon-derived PDRN + exosomes + low-molecular collagen straight into your pores — offering a “microneedling in a bottle” effect.

  • Deep Skin Renewal: PDRN + exosomes boost regeneration and smooth texture without actual needles.
  • Firmer, bouncier skin: Collagen and peptides improve elasticity and tighten overall skin appearance.
  • Brighter tone & smaller-looking pores: Niacinamide and exosomes even skin tone and refine pores for a clearer glow.
Volume

30ml

Main Ingredients

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Treatment area

Intended Use

Tone-up, Blemish Care, Elasticity, Hydration, Skin Texture Improvement, Pore Care, Skin Regeneration

Skin Type

All Skin Types

Disclaimer: Products on our website are intended for use by qualified healthcare professionals only.

We are not responsible for any adverse effects from self-administration or for compensation of wasted or misused products.

The information on this page is not a substitute for professional medical advice, diagnosis or treatment. Always consult a professional healthcare provider for a personalized medical guidance.

Main Benefits

High-Purity Skin Renewal Support

The serum helps improve overall skin texture, supporting smoother, more even-looking skin with a healthier glow.

Advanced Pore & Tone Refinement

It works on dullness, visible pores, and uneven tone—promoting clearer, brighter, glass-like radiance.

Elasticity & Firmness Booster

Enhances bounciness and skin elasticity, giving a firmer, more lifted appearance over time.

Daily Use, Low-Irritation Formula

Designed for everyday use—no stickiness, no artificial coloring, and clinically tested for low irritation.

Medicube PDRN Pink Collagen Exosome Shot 2000 is a daily skin-booster serum designed to deliver deep renewal and visible radiance through a blend of Salmon DNA PDRN, exosomes, and ultra-low molecular collagen. 

PDRN is a purified DNA extract from salmon known for its strong compatibility with human skin, helping support natural regeneration and resilience. Combined with high-purity exosomes and collagen, the formula targets texture, elasticity, and clarity—creating a smoother, brighter, and more refined complexion with continued use.

Indications

Medicube PDRN Pink Collagen Exosome Shot Serum is ideal for individuals who want to improve skin texture, boost radiance, and enhance elasticity through a daily, low-irritation “microneedling-in-a-bottle” formula.

Refine uneven skin texture for a smoother, more polished appearance.

Brighten dull or tired-looking skin to promote a clearer, healthier glow.

Support elasticity and firmness for bouncier, more youthful-looking skin.

Improve the look of enlarged pores and help maintain a refined complexion.

Even out tone and discoloration, including stubborn uneven patches.

Provide lightweight hydration while supporting overall skin resilience.

Active Ingredients

Salmon PDRN

Extracted and refined for cosmetic use due to their strong compatibility with human skin.

Exosomes

Derived from cultured stem cell–based systems used in cosmetics.

Collagen

Broken down into ultra-small molecules to improve absorption and support elasticity.

Niacinamide

Brightens dull skin, improves elasticity, and supports balanced oil production.

Spicules (2,000 PPM)

Refined into micro-particles to create the signature tingling and enhanced absorption effect.

Purity and Safety

Medicube PDRN Pink Collagen Exosome Shot Serum is formulated with high-purity ingredients, including 99% purified Salmon PDRN, 15M refined exosomes, and ultra-low molecular collagen, all processed to meet cosmetic-grade safety standards. Its natural pink hue comes from the raw materials themselves, with no artificial coloring added. 

The lightweight, low-irritation formula is designed for daily use, and the signature tingling sensation comes from naturally derived spicules that enhance absorption without damaging the skin barrier. While compatible with most skincare routines, users with sensitive skin are encouraged to patch test and adjust usage based on comfort.

Mechanism of Action

The PDRN Pink Collagen Exosome Shot Serum works by combining PDRN, exosomes, ultra-low molecular collagen, and spicules to promote deeper delivery and visible skin renewal. The naturally derived spicules create a gentle, microneedling-like sensation on the surface of the skin, helping active ingredients travel more effectively into the pores.

  1. PDRN supports the skin’s natural regenerative processes, improving texture and resilience over time.
  2. Exosomes act as communication carriers, helping brighten, refine pores, and encourage healthier skin turnover.
  3. Low-molecular collagen absorbs quickly to support elasticity and firmness, while niacinamide helps even tone and strengthen the skin barrier.

Together, these components work in layers to smooth texture, boost radiance, and enhance overall skin clarity with continued use.

What Makes Medicube PDRN Pink Collagen Exosome Shot Serum Different?

Medicube PDRN Pink Collagen Exosome Shot Serum stands out for its unique “microneedling-in-a-bottle” approach, delivering active ingredients deeper through naturally derived spicules instead of physical needles.

Unlike typical brightening or collagen serums, it combines 99% purified Salmon PDRN, 15M high-purity exosomes, and ultra-low molecular collagen in one formula, targeting regeneration, elasticity, and clarity at the same time. Its natural pink color comes from the raw materials themselves—no artificial dyes—and its watery, low-irritation texture makes it suitable for daily use. The spicules create a temporary tingling sensation that enhances absorption, helping the skin appear smoother, firmer, and more refined with consistent use.

Treatment Areas

This serum is intended for overall facial use and targets the areas most commonly affected by rough texture, enlarged pores, dullness, and reduced elasticity.

  • Full Face
    For comprehensive improvement in smoothness, radiance, and skin clarity.
  • Forehead
    Helps soften rough patches and brighten dull, uneven skin.
  • Cheeks
    Addresses visible pores, loss of bounce, and surface dullness.
  • Nose Area
    Supports pore refinement and smoother, more even texture.
  • Chin & Jawline
    Helps improve clarity and unevenness in areas prone to congestion.
  • Neck (optional)
    Can be used to maintain brightness and firmness if the skin tolerates spicules well.

Preparations Before Use

  1. Cleanse thoroughly
    Start with a clean face to ensure the serum can absorb properly and the spicules can contact the skin evenly.
  2. Dry the skin completely
    Make sure the skin is fully dry before application; applying on damp skin may increase sensitivity.
  3. Avoid the eye and lip areas
    These areas are thinner and more delicate, and may react strongly to spicules.
  4. Patch test if sensitive
    For first-time users or those with reactive skin, apply a small amount to a test area and wait 24 hours to assess tolerance.
  5. Pause other strong actives
    If you regularly use acids, retinoids, or scrubs, consider reducing frequency to prevent unnecessary irritation.
  6. Prepare a simple routine afterward
    Have a lightweight, water-based moisturizer ready for post-application comfort.

Contraindications

Medicube PDRN Pink Collagen Exosome Shot Serum should be used with caution or avoided in the following cases:

  • Active skin irritation or inflammation
    Avoid applying on sunburned, peeling, or sensitized skin.
  • Open wounds or compromised barrier
    Do not use on areas with cuts, scratches, or healing lesions.
  • Hypersensitivity to spicule-based products
    Those who react strongly to micro-particle formulas may experience increased discomfort.
  • Allergies to key ingredients
    Discontinue or avoid use if you have known sensitivities to ingredients such as Salmon PDRN, collagen, niacinamide, or marine-derived spicules.
  • Recent strong exfoliation or procedures
    Use caution if you recently applied strong acids, retinoids, or underwent peels/laser treatments.
  • Highly reactive or very sensitive skin
    If you cannot tolerate tingling, heat, or prolonged redness, this product may not be suitable.

How to Use

Step 1 — Apply on clean, dry skin

After cleansing, dispense an appropriate amount and spread evenly across the face, avoiding the eye and lip areas.

Step 2 — Press gently for absorption

Use your fingertips to lightly press and smooth the serum into the skin. The tingling sensation from the spicules is expected as they help deliver the ingredients more effectively.

Step 3 — Follow with a simple moisturizer

Finish with a lightweight, water-based moisturizer or your usual hydrating serum/cream to keep the skin comfortable.

Step 4 — Adjust frequency based on tolerance

Start with fewer uses per week if you are new to spicule-based products, then increase as your skin adapts.

What to Do After Applying?

Keep the serum on the skin
Do not rinse it off; the formula is designed to remain on the skin so the spicules can deliver active ingredients effectively.

Follow with lightweight hydration
Use a simple, water-based moisturizer or your regular PDRN cream to keep the skin comfortable as the tingling sensation settles.

Avoid strong actives for the day
Pause acids, retinoids, scrubs, or other intensive treatments to prevent unnecessary irritation.

Minimize friction
Avoid rubbing, scratching, or using cleansing devices on the treated area, as the spicules remain in the skin for several hours.

Use sunscreen during the day
Protect the skin with a broad-spectrum SPF if used in the morning, as renewed skin can be more sensitive to sunlight.

Before and After

What's Inside

1 × Medicube PDRN Pink Collagen Exosome Shot Serum (30 mL)

Full-size bottle designed for daily use, featuring 99% purified Salmon PDRN, 15M exosomes, and ultra-low molecular collagen.

FAQ

The serum contains naturally derived spicules that create a gentle, microneedling-like sensation. This helps the active ingredients travel deeper into the pores. The tingling, warmth, or mild redness is expected and usually settles over time.

No. This serum stays on the skin to keep delivering its benefits. Simply let it absorb and follow with your moisturizer.

It’s generally compatible with most routines, but if you use strong actives (like acids or retinoids), it’s better to space them out or reduce frequency to avoid irritation.

It’s low-irritation, but sensitive skin may react more strongly to spicules. A patch test is recommended, and you can adjust usage based on comfort.

You can start slowly—2–3 times a week—and increase frequency as your skin adjusts. Daily use is possible once tolerance is built.

They don’t stay permanently. The spicules naturally shed along with dead skin cells over the next few days.

How to Store

  • Store the serum in a cool, dry place, away from direct sunlight and heat exposure.

  • Keep the bottle tightly closed when not in use to maintain freshness.

  • Avoid storing in humid areas like bathrooms, as moisture may affect the formula.

  • Keep out of reach of children.

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