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Puri COLL RH is a skin-boosting collagen formula designed to support skin firmness, elasticity, and overall skin quality. It combines Recombinant Human Collagen (RH-Collagen) with Hyaluronic Acid to help skin look smoother, more hydrated, and more resilient. The focus is on improving skin texture and vitality, rather than adding volume.

  • Improved Skin Firmness & Elasticity: Supports skin structure and resilience, helping skin appear firmer and more supple.
  • Deep Hydration and Comfort: Hyaluronic Acid helps maintain optimal moisture levels, improving softness and smoothness.
  • Refined Skin Texture: Helps improve the appearance of uneven texture for a smoother, healthier-looking complexion.

Disclaimer: Products on our website are intended for use by qualified healthcare professionals only.

We are not responsible for any adverse effects from self-administration or for compensation of wasted or misused products.

The information on this page is not a substitute for professional medical advice, diagnosis or treatment. Always consult a professional healthcare provider for a personalized medical guidance.

Main Benefits

100% Human-Identical Recombinant Collagen (Type I & III)

Provides superior biocompatibility with reduced risk of immune reaction, ensuring safe integration into the skin.

Immediate Lifting with Structural Support

Type I collagen forms a supportive dermal scaffold, delivering visible tightening and contour support shortly after treatment.

Long-Term Skin Regeneration & Elasticity Improvement

Type III collagen, PDRN, and peptides activate fibroblasts to stimulate sustained collagen production and dermal renewal.

Enhanced Skin Firmness, Density & Texture

Improves skin resilience, smoothness, and overall quality across face, neck, hands, and body areas.

Advanced Multi-Active Regenerative Formula

Hyaluronic acid hydrates, succinic acid boosts fibroblast activity, and multi-peptides support wrinkle reduction and skin strengthening.

Animal-Free, High-Purity Biotech Manufacturing

Produced using recombinant DNA technology under strict controls, ensuring consistent quality, ethical sourcing, and premium clinical outcomes.

Indications

PURI COLL Rh is indicated for skin regeneration, lifting, and elasticity improvement in areas affected by collagen loss, skin laxity, and textural aging, including:

Fine lines and wrinkles on the face

Nasolabial folds and marionette lines

Crow’s feet and forehead lines

Under-eye wrinkles, dark circles, and eye bags

Neck and décolletage wrinkles

Hand and arm rejuvenation

Ingredients

Recombinant Human Collagen Type I

Deliver immediate surface hydration while supporting deeper, longer-lasting moisture retention.

Recombinant Human Collagen Type III

Supports long-term skin regeneration and elasticity by stimulating fibroblast activity and promoting healthy collagen remodeling.

Hyaluronic Acid (HA)

Enhances hydration and skin suppleness while creating optimal conditions for collagen formation and tissue repair.

PDRN (Polydeoxyribonucleotide)

Encourages cellular repair and regeneration by activating fibroblasts and supporting DNA-level skin recovery.

Succinic Acid

Supports long-term skin regeneration and elasticity by stimulating fibroblast activity and promoting healthy collagen remodeling.

Multi-Peptides Complex

Targets skin firming and wrinkle reduction by supporting collagen signaling, antioxidant protection, and dermal structure reinforcement.

Mechanism of Action

PURI COLL Rh works through a dual regenerative mechanism that delivers both immediate support and long-term skin renewal.

    • Structural Collagen Support
      Recombinant Human Collagen Type I integrates into the dermal matrix to form a supportive scaffold, helping improve skin firmness, lifting, and density shortly after application.
    • Regenerative Collagen Stimulation
      Recombinant Human Collagen Type III activates fibroblasts to stimulate natural collagen and elastin production, supporting ongoing tissue regeneration and elasticity improvement.
    • Cellular Repair & Fibroblast Activation
      PDRN promotes DNA-level tissue repair and cellular recovery, while succinic acid enhances fibroblast activity to accelerate collagen synthesis.
    • Hydration & Optimal Healing Environment
      Hyaluronic acid deeply hydrates the skin, improving suppleness and creating ideal conditions for collagen remodeling and tissue renewal.
    • Peptide Signaling for Skin Strengthening
      Multi-peptides support collagen signaling pathways, helping improve skin structure, firmness, and wrinkle appearance over time.
    • Together, these mechanisms provide visible lifting, improved skin quality, and progressive dermal regeneration with minimal downtime.

Product Preparation

PURI COLL Rh is supplied ready to use and does not require reconstitution.

    • Inspect the product before use to ensure the solution is clear and free from visible particles.

    • Allow the product to reach room temperature prior to application for optimal handling.

    • Select appropriate application tools according to the chosen technique and treatment area.

    • Prepare the treatment area using standard antiseptic skin cleansing protocols.

    • Use immediately after opening. This product is intended for single use only.

Do not store or reuse any remaining product after opening.

Treatment areas

Puri COLL rh treatment areas

Dosage and technique

PURI COLL Rh is intended for professional aesthetic use and should be applied according to established protocols.

Treatment Method
  • Manual application technique
    Suitable for controlled placement at a depth of approximately 2–3 mm, following practitioner protocol.

  • Retrograde linear technique
    Applied using a flexible delivery device, typically 38–50 mm in length, depending on the treatment area and approach.

Application Depth
  • Deep dermis (approximately 2–3.5 mm)
    Targets the collagen-dense layer where regeneration and extracellular matrix (ECM) remodeling are most active.

Post-treatment

  • Lips may feel more hydrated and comfortable shortly after application.

  • Mild redness or warmth can occur and typically resolves on its own.

  • Avoid excessive heat, alcohol intake, or aggressive lip products immediately after treatment.

  • Keep lips moisturized and avoid excessive manipulation of the area.

  • Maintain good hydration to support optimal and longer-lasting results.

Course of Treatments

2

Sessions

A standard course consists of 2 sessions, performed 1 month apart to support both immediate and progressive skin improvement.

1

Month

The interval between sessions allows the skin to respond gradually, supporting collagen and elastin stimulation.

3–4

Months

After 3–4 months, an additional 2-session course may be performed at 1-month intervals to maintain and enhance results.

How quickly will the result appear?

Immediately

Immediate effects such as volumizing, lifting, and wrinkle improvement may be observed after the first session, with continued improvement in skin density and firmness following subsequent sessions.

Before & Afters

What's Inside

  • 1 pre-filled unit containing 2.5 mL of PURI COLL Rh

  • 1 box

FAQ

PURI COLL Rh is designed to support skin regeneration, firmness, and elasticity by providing human-identical recombinant collagen alongside regenerative support ingredients.

Some effects such as volumizing and lifting may be noticed immediately after the first session, with continued improvement in skin density and firmness over time.

A standard course consists of two sessions spaced one month apart, with an additional course recommended after 3–4 months if maintenance or enhancement is desired.

PURI COLL Rh is suitable for areas such as nasolabial folds, crow’s feet, forehead lines, marionette lines, under-eye bags, neck and décolletage wrinkles, hands and arms, as well as elbows and knees.

No. PURI COLL Rh is produced using recombinant DNA technology and is 100% human-identical, with no animal-derived components.

PURI COLL Rh is designed for minimal downtime, allowing individuals to resume normal activities shortly after treatment, following practitioner after-care guidance.

Contraindications

PURI COLL Rh should not be used in the following cases:

  • Known hypersensitivity or allergy to any of the product components

  • Active infection, inflammation, or skin disease at the treatment site

  • Pregnancy or breastfeeding, unless deemed appropriate by the practitioner

This product is intended for professional aesthetic use only. Proper training, technique, and patient assessment are required prior to application.

How to store

  • Store them in a cool, dry place, away from direct sunlight or heat.
  • Avoid exposing the product to extreme temperatures.
  • Do not freeze.
  • Keep the product sealed until use
Please note that our products are intended for use by qualified medical professionals only. We accept no responsibility for any adverse effects or complications resulting from self-administration or misuse. Furthermore, we do not provide compensation for products that have been wasted, damaged, or otherwise improperly used.

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