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Botulax 100U is a botulinum toxin type A used by licensed professionals to reduce the appearance of facial wrinkles and fine lines. It works by temporarily relaxing targeted muscles, making it a popular option for aesthetic treatments. Manufactured in South Korea by Hugel, Inc., Botulax is known for its high purity, consistent potency, and reliable results. It's commonly used for glabellar lines, blepharospasm, and muscle spasticity.
Main Benefits of Botulax 100U
Smooths Wrinkles and Fine Lines
Botulax helps relax facial muscles, reducing the appearance of expression lines like frown lines and crow’s feet.
High Purity and Quality
With over 99% purity, Botulax is known for its clean formulation and consistent results.
Clinically Tested and Safe
Proven in clinical trials to be safe and effective, with comparable results to other well-known brands.
Fast-Acting and Long-Lasting
Results typically appear within a few days and can last several months, depending on the treatment area and individual.
Indications
Botulax 100U is primarily used by medical professionals for aesthetic and therapeutic purposes. It helps reduce muscle activity to soften wrinkles and improve specific muscle-related conditions.
-
Facial Rejuvenation
Helps create a more youthful and relaxed appearance by targeting overactive facial muscles. -
Muscle Relaxation
Temporarily relaxes facial muscles that cause visible lines, preventing the deepening of wrinkles over time. -
Therapeutic Use
Approved for treating conditions like blepharospasm (involuntary eye twitching) and muscle spasticity. -
Common Treatment Areas
Forehead, between the eyebrows, around the eyes, lower face, and neck.
How is Botulax made
Botulax 100U is manufactured by Hugel, Inc. in South Korea using high-quality standards and advanced purification processes. The active ingredient is Clostridium Botulinum Toxin Type A, which is purified to over 99% purity using Size Exclusion High Performance Liquid Chromatography (SE-HPLC). This ensures high safety and consistent potency.
The final product is a fine, freeze-dried powder that comes in a sterile vial containing 100 units of botulinum toxin type A. It is reconstituted with 0.9% saline before use.
Botulax has been tested for stability, efficacy, and safety, showing comparable results to other leading brands in multiple clinical trials. It is produced under strict quality control and remains stable when stored at 2–8°C.
What Botulax is made of
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Clostridium Botulinum Toxin Type A (100U)
A purified neurotoxic protein that temporarily blocks nerve signals to targeted muscles, reducing the appearance of dynamic facial wrinkles. -
Human Serum Albumin (0.5 mg)
A protein derived from human blood plasma, used to stabilize the toxin and maintain its effectiveness after reconstitution. -
Sodium Chloride (0.9 mg)
Commonly known as salt, this helps balance the solution's pH and tonicity for safe injection.
Mechanism of action
Botulax 100U works by temporarily blocking nerve signals to targeted muscles. When injected, the Clostridium Botulinum Toxin Type A prevents the release of a neurotransmitter called acetylcholine, which is responsible for triggering muscle contractions.
By stopping these signals, the treated muscles relax, reducing the movement that causes wrinkles, especially those formed by repeated facial expressions like frowning or squinting. This muscle relaxation smooths out the skin, softens expression lines, and creates a more refreshed appearance.
When used correctly by trained professionals, the effect is localized to the injected area and does not spread throughout the body.
Why does Botulax 100U look Empty? (Video Explanation)
Product preparation
Botulax 100U comes as a fine, freeze-dried powder that must be reconstituted with saline before use. Proper preparation ensures safe and effective application.
Materials Needed:
0.9% sterile saline
Sterile 30G 0.5cc insulin syringe
Latex gloves
Alcohol swabs
Preparation Steps:
Use 0.9% Sodium Chloride (saline) to dilute the product.
Draw the desired amount of saline into a syringe and slowly inject it into the vial containing Botulax 100U.
Gently swirl the vial to mix. Do not shake vigorously.
The reconstituted solution should be clear and free of particles.
Store in a refrigerator (2–8℃) and use within 24 hours. Although manufacturers recommend 24 hours, research indicates stability for up to 5 weeks under proper refrigeration.
How to dilute Botulax 100U
Botulax comes in a vial containing a fine, freeze-dried powder containing 200 units of Botulinum toxin type A that needs to be diluted with 0.9% saline.
Note: The powder is very fine, so the vial may look empty. Rest assured that all units are present.
|
Diluent Added (0.9% Sodium Chloride) |
|
|---|---|
|
Botulax® 100U |
Resulting Dose (U/0.1 mL) |
|
1.0mL |
10U |
|
2.0mL |
5U |
|
2.5mL |
4U |
|
4.0mL |
2.5U |
Step-by-Step Dilution Instructions:- Follow the following steps to dilute & reconstitute your toxin.
- Take the vial out of the refrigerator and visually inspect: the vial should be colorless and transparent with a small quantity of white/light yellow freeze-dried powder.
- Using the table below, draw Saline (0.9% Sodium Chloride) into a syringe and slowly add it to the vial.
- Gently and slowly swirl the vial to mix, do not shake excessively.
- The reconstituted product should be kept in the refrigerator (2-8℃) and used within 24 hours
Note: Manufacturers recommend using the toxin within 24 hours of dilution, but research has shown that the reconstituted product remains stable for up to 5 weeks in the refrigerator (2-8℃).
Treatment areas
Botulax 100U is commonly used by professionals to target facial expression lines and certain muscle-related conditions.
Face
Glabellar lines (between the eyebrows)
Forehead lines
Crow’s feet (outer corners of the eyes)
Lower face and jawline (for muscle contouring)
Around the eyes (for blepharospasm treatment)
Body
Areas affected by muscle spasticity
Upper limbs (used in post-stroke upper limb spasticity)
Lower limbs (e.g., equinus foot deformity in children with cerebral palsy)
Dosage and technique
Botulax 100U should only be administered by licensed medical professionals trained in botulinum toxin injections. Dosage and injection technique may vary depending on the treatment area and the individual’s condition.
General Guidelines
For benign essential blepharospasm: Injected into the muscles surrounding the eyes in adult patients.
For post-stroke upper limb spasticity: Injected into affected muscle groups in patients aged 20 or older.
For equinus foot deformity in children with cerebral palsy: Administered to lower limb muscles in children aged 2 years and older.
For glabellar lines (frown lines): Used to treat moderate to severe wrinkles between the eyebrows caused by repeated facial expressions.
Post-treatment
Do Not Rub or Massage the Treated Area
Avoid massaging or applying pressure to the injection site for at least 24 hours, unless instructed otherwise by your provider.Stay Upright
Remain upright and avoid lying down for 4–6 hours after treatment to help prevent the toxin from migrating to other areas.Avoid Strenuous Activity
Refrain from intense exercise or physical exertion for 24–48 hours after treatment.Skip Heat Exposure
Avoid hot tubs, saunas, steam rooms, or excessive sun exposure for at least 24 hours, as heat may increase swelling or bruising.Delay Facial Treatments
Do not get facials, microdermabrasion, or chemical peels for at least 1 week post-treatment.Monitor for Side Effects
Mild redness, swelling, or bruising at the injection site is common and usually resolves within a few days. Contact your provider if you experience persistent discomfort or unexpected symptoms.
Course of Treatments
How quickly will the result appear?
Before & Afters
What's Inside
Each Botulax 100U kit includes:
1 vial of Botulax 100U (freeze-dried Botulinum Toxin Type A)
1 insulin syringe (30g, 8mm, 0.5cc)
0.9% saline for dilution
1 pair of latex gloves
Alcohol swabs
FAQ
No, results are not immediate. Most people begin to notice changes within a few weeks after treatment. Clinical studies showed improvements during follow-ups at 4, 6, and 12 weeks.
Most patients experience minimal discomfort. A fine needle is used, and the process is quick. Mild redness or swelling at the injection site may occur.
The procedure is usually done in minutes. After treatment, you may experience mild swelling or redness, which usually goes away quickly. Avoid rubbing the area or lying down for several hours.
You can return to most normal activities right after treatment. Avoid intense exercise, heat exposure, or facial treatments for at least 24–48 hours.
Makeup can usually be applied a few hours after treatment, as long as you avoid pressing or rubbing the treated area.
Yes, Botulax 100U is available at wholesale pricing for licensed aesthetic practitioners and medical clinics. Our wholesale program supports high-volume practices with competitive rates and reliable product sourcing. Wholesale ordering ensures your practice has consistent access to quality botulinum toxin. Apply for wholesale access through our Wholesale Application portal.
How to properly store
Store unopened vials in a refrigerator at 2–8°C (35.6–46.4°F).
Do not freeze.
Once reconstituted, the solution must be kept refrigerated and used within 24 hours.
Protect from light and do not use if the solution appears discolored or contains particles.
Do not use beyond the expiration date printed on the vial.
Botulax 100U is intended for use by licensed medical professionals only. Improper storage or handling may affect product quality. We are not responsible for outcomes resulting from misuse, improper administration, or storage outside the recommended conditions.
Better than when I go to my esthetician
Product Benefits Fine lines, wrinkles
Age 38
I saw results so fast with this, this is my fave tox to use so far
Perfect
Love the product 👌