Elasty D Plus X3 Set

PNET (Preserved Natural Entanglement Technology) is an advanced cross-linking process used in the production of certain hyaluronic acid dermal fillers. Here’s a simplified summary:

1. Cross-Linking Process: PNET involves a specialized method of cross-linking, where the aim is to achieve ideal cross-linking. In this context, “cross-linking” refers to the process of chemically bonding molecules to form a more stable and cohesive structure.

2. Ideal Cross-Linking: The goal is for 100% of the BDDE (a cross-linking agent) to participate in the cross-linking process, leaving no unlinked BDDE. This is significant because partially linked or unlinked BDDE (referred to as “Open cross-linked”) can potentially cause adverse events.

3. FDA Guidelines Compliance: The PNET technology ensures compliance with stringent FDA guidelines, which dictate that the level of Open cross-linked or non-cross-linked BDDE should be below 2 ppm (parts per million).

4. Increased Crosslinking Efficacy: By utilizing lower amounts of BDDE, PNET increases the efficacy of crosslinking. This minimizes the presence of inactive Open-cross linked BDDE.

5. Dual Cleaning Process: PNET incorporates a two-stage cleaning process. The first cleaning step inactivates any Open-cross linked BDDE, and the second cleaning step effectively eliminates free BDDE.

In essence, PNET technology enhances the safety and effectiveness of dermal fillers by ensuring a more efficient and cleaner cross-linking process, aligning with safety standards and minimizing the risk of adverse effects.