Modern injectable rejuvenation techniques are a good alternative to plastic surgery. Beauty injections of botox treatment allow you to preserve youth and beauty without the risk of complications that occur after plastic surgery. The undeniable advantages of injection techniques are a quick result, no recovery period and ample opportunities.
In this article, we will take an in-depth look at what Botox is, what the best Korean botox brands in 2023 are, and how to choose which Botox brands are best for you.
Table of Contents
What is Botox?
Botox is the very first drug, rightfully called the “standard of botulinum therapy”.
In essence, Botox is an injection that helps reduce facial lines and wrinkles. For cosmetic purposes, Botox is most commonly used to reduce the appearance of smile lines, forehead wrinkles, and crow’s feet.
Botox contains purified botulinum toxin type A combined with human serum albumin (0.5 mg) and sodium chloride (0.9 mg). Due to the large molecule size of 900 kDa and albumin concentration (average among other drugs), Botox has a fairly limited diffusion and allows you to achieve the expected result even at difficult injection points, its action is always predictable. This allows you to avoid complications, side effects and maintain a natural facial expression.
In 1989, the FDA officially approved the use of Botox for the treatment of a number of diseases associated with involuntary muscle contractions. And although wrinkles were not yet on the list of indications for the use of this drug, more and more doctors began to use this medicine, as they say, “off label”, that is, not for its intended purpose.
Only in 2002, the FDA finally approved the use of Botox (Botox® Cosmetic) for cosmetic purposes - to eliminate facial wrinkles on the forehead and around the eyes. From that moment began the triumphant ascent of Botox to the pinnacle of success. It got to the point that in the United States this procedure has become so popular that it is offered almost at every turn - in beauty salons and even in sports clubs.
A bit of theory about botulinum toxins in cosmetology
The basis of Botox - Botulinum toxin type A is a polypeptide that has been widely used in clinical medicine in the past two decades. Today, more than 100 potential indications for the therapeutic use of botulinum toxin type A are known. Hundreds of scientific articles and guidelines have been published on the clinical use of botulinum toxin. Millions of patients have been treated. Currently, this unique drug is used in the clinical practice of doctors of various specialties: neurologists, cosmetologists, dermatologists, plastic surgeons, ophthalmologists, dentists, orthopedists, orthodontists, otolaryngologists, oncologists, rehabilitation specialists, gastroenterologists, urologists, proctologists, gynecologists, even psychotherapists.
The unique mechanism of action of botulinum toxin type A, the locality of action, the possibility of injection into any accessible area, good treatment tolerance, safety, absence of systemic side effects and long duration of action, proven on the basis of rigorous scientific studies, determine the therapeutic value of botulinum toxin.
Where do wrinkles come from and why do they disappear after botulinum toxin injections
Wrinkles, which so upset women, not only look different, but have different causes.
True age wrinkles arise due to changes occurring in the skin itself. Everything you've heard about collagen breakdown and the accumulation of damage from UV radiation and other harmful factors applies to this type of wrinkle.
But there are other wrinkles, which are just skin folds that form at the site of the usual spasm of the subcutaneous muscles. When contracting, the muscle shortens and wrinkles the skin, and when relaxed, it returns to its original position and “pulls” it back with it. In young women, the skin is elastic, it quickly reacts to such muscle movements and recovers, but with age, such exercises are already harder for her.
So, how to stop muscle from moving? The answer is to relax it! If you can force the muscle to completely relax, then the wrinkle is smoothed out as if by magic. And luckily for us, botulinum toxin can do this.
The effect, as a rule, lasts 3-4 months, after which the muscle activity is restored and the fold returns to its original place. Therefore, botox injections need to be repeated from time to time.
- How Botox prevents muscles to move?
Muscle contraction starts with a series of actions at the nerve ending, where special structures called synaptic vesicles merge with the muscle.
This process releases chemicals that cause the muscle to contract, creating wrinkles. Botox works by interrupting this process, reducing the muscle contractions that lead to wrinkles.
Most Popular Korean botox Injections in 2023
As we have already found out, original Botox was the first anti-wrinkle product with botulinum toxin type A in the composition. But Korean manufacturers did not stand aside and offered their high-quality, and sometimes innovative brands of botox, which are high-quality analogues and are not inferior in their properties to their legendary progenitor Botox from Allergan.
Now there are quite a lot of Korean brands for botox treatment on the market and it can be quite difficult to decide on the choice of one or another brand.
Among the wide variety of Korean botox, there are brands that have declared themselves for a long time and are represented in many countries, such as Botulax, Nabota, Neuronox & Meditoxin, Innotox. But in recent years, thanks to the popularity of the Botox injection procedure, new Korean botox such as Liztox, Hutox, ReNTox began to appear, the popularity of which, along with the trust of estheticians around the world, is growing every day. Recently, completely new brands have appeared, such as Wondertox, Wellstox, Coretox, Ellelux and others.
So how to make the right choice, what brand of Botox is the best? Next, we will look at each botox Korean brand separately and, as a result, we will try to answer the question which brand is best for you?
1. Botulax
Botulax is a botulinum toxin type A preparation developed by one of the largest and most famous South Korean manufacturers, Hugel. Perhaps Botulax is one of the most recognizable Korean botox around the world and rightfully can be called the best botox. Botulax has passed all the necessary clinical studies and is one of the analogues of drugs containing botulinum toxin type A. The composition is identical to that of the original Botox. Botulax contains only three components - human albumin, botulinum toxin type A and saline. These substances are perfectly accepted by the body, there is no risk of rejection and therefore allergic reactions are excluded even theoretically.
The advantage of Botulax is the inability to penetrate into neighboring tissues due to its high molecular weight and medium concentration of albumin. Botulax is widely used to smooth mimic wrinkles and temporarily correct hyperhidrosis.
The first results after the introduction of Botulax can be assessed already on the 3rd day, and the maximum effect is achieved on the 14th day. Appearance after rejuvenation will be maintained for 4-6 months. Release form for 100 units and 200 units.
2. Liztox
Liztox is another analogue of Botox from the South Korean manufacturer Huon’s Global, which is quickly gaining its popularity in the markets of a large number of countries and for good reason. Liztox is a Clostridium botulinum type A toxin with a high purity of 99.8%. This level is considered a new quality standard in the world market. Liztox is a peripherally acting muscle relaxation and provides long-term wrinkle correction.
Liztox is designed to improve moderate, heavy, and deep muscle lines associated with the brow muscles and active facial muscles in adults.
The main advantages of Liztox include a quick and noticeable effect of the procedure, its long-term effect, as well as a loyal cost.
Release form for 100 units and 200 units.
3. Nabota
Nabota is a botulinum toxin type A formulation developed by the South Korean manufacturer Daewoong. It is a highly purified product, manufactured using a proprietary process to ensure maximum removal of impurities. Nabota 100U is safe, all natural and easy to use. In the US, Nabota is better known under the Jeuveau brand, which received FDA approval in February 2019 and is the same product.
Nabota has proven amazing results in eliminating wrinkles and preventing their appearance in problem areas of the face in adults aged 20 to 65 years.
Nabota is highly safe, does not freeze facial expressions, and is commonly used to treat brow wrinkles, the vertical lines that appear between the eyebrows.
The Nabota brand has long been known around the world and deservedly receives laudatory reviews from the most demanding professionals in the cosmetology industry.
Results can be seen approximately two days after the injection, and it may take up to 10 days to obtain the final result, and the resulting effect lasts at least six months.
Release form for 100 and 200 units.
4. Innotox
Innotox is an innovative premium preparation of botulinum toxin type A developed by the well-known South Korean company Medytox Inc. Meditox Inc. is one of the world’s largest and best biopharmaceutical companies and has won the respect of customers with its high quality products.
Unlike the world famous Botox, Innotox has a liquid dosage form (ready to use and does not require dilution) and an improved formula. It is popular in many countries of the world due to its ease of use, high efficiency and low cost.
Most often, Innotox is used to eliminate many cosmetic problems such as blepharospasm, hemifacial spasm, spastic torticollis, mimic wrinkles, bunny lines, excessive sweating of the palms and armpits, brow furrow, nasolabial folds, wrinkles around the mouth and mesobotox treatment.
With the help of Innotox, you can correct the shape of the nose and face oval, correct errors in the position of the lips, expressed in the constant elevation of both parts.
The first result after Innotox treatment is visible after 3-5 days, the maximum effect is achieved after a couple of weeks and lasts up to six months.
The Innotox developers believe that liquid formulations will be easier to work with and avoid errors and loss of potency when reconstituting the lyophilisate and diluting the solution, as with other toxins that are presented in powder form.
Release form for 25 units, 50 units, 100 units.
5. ReNTox
Rentox (ReNTox 100 units) is also a premium botulinum toxin type A drug with unique properties, produced by the South Korean company Pharma Research BIO Co., Ltd. This drug has gained great popularity in many countries of the world due to its high efficiency and low cost.
Most often, this drug is used to correct dynamic wrinkles on the face – in the forehead and between the eyebrows, vertical wrinkles on the lips, “puppet wrinkles” in the corners of the mouth and to effectively eliminate “crow’s feet” in the corners of the eyes.
Rentox can also be used to reduce the severity of nasolabial folds when smiling, with facial paralysis and facial asymmetry, as well as with hyperhidrosis of the face, hands and armpits.
Release form for 100 units and 200 units.
6. Meditoxin and Neuronox
Both Meditoxin and Neuronox botulinum toxin type A toxins are called the South Korean analogue of the Botox drug from the renowned Korean manufacturer Medytox. Meditoxin and Neuronox are also very similar to the American Botox, both in therapeutic action and in their composition. But there is also a difference. It lies in the rather low degree of permeability of Meditoxin and Neuronox into the surrounding tissues. Due to its low diffusion, Meditoxin and Neuronox can be used in delicate areas. For example, in the area of the eyes or lips. The botulinum toxin included in the formulation of Meditoxin and Neuronox has a high molecular weight. Thanks to Meditoxin and Neuronox, it is possible to work out areas with small mimic wrinkles. He acts very delicately and carefully.
A noticeable result is achieved after 1-2 days after the injection. Due to the low degree of diffusion into the surrounding tissues, complete clinical safety for the body is achieved. Meditoxin and Neuronox have a mild and correct effect without pain and discomfort after the procedure. Meditoxin and Neuronox are also great for treating excessive sweating or hyperhidrosis.
Release form for 100 units and 200 units.
7. Toxsta
Korean company Jetema Co. released the long-awaited new product. Toxsta entered the beauty market not so long ago, but has already become a favorite of specialists. Toxsta is absolutely no different in composition and dosage from other Korean analogues, however, the quality is excellent (99.8% purity) and has a low risk of immunogenicity.
Toxta is the original strain of the European National Institute. It is a high purity product with a low risk of immunogenicity that complies with cGMP (FDA, EMA) standards for safe and fast wrinkle smoothing and long lasting lip contouring.
The main ingredient of the drug is Clostridium botulinum type A. It is produced using innovative vacuum drying technology. Has an instant, consistent effect. The drug has passed dermatological tests, completely safe for humans.
Release form for 100 units.
8. Wondertox
Wondertox is a new brand introduced to the market by Chong Kun Dang that has been carefully tested to ensure safe use.
Wondertox is used to inhibit muscle contraction to remove deep wrinkles and fine lines. Wondertox is FDA approved making it safe to use. Wondertox effectively removes fine and deep wrinkles, has a smoothing effect on the skin, so that your skin looks flawlessly young.
If you are looking to buy botulinum toxin with high quality included at a very affordable price Wondertox might be a really great choice.
Release form for 100 and 200 units.
9. Coretox
The Korean company Medytox has developed Coretox, which also includes a toxin without complexing proteins. To stabilize the toxin, sodium chloride and surfactants are used, which allows to reduce the effective dose and, thus, improve the pharmacoeconomics of therapy and further increase its safety by reducing the risk of developing immunoresistance.
Release form for 100 units.
10. Ellelux
Ellelux can be attributed to another completely new brand of Korean Botox. The advantages include the reliability and high standards of production of the Korean pharmaceutical company Biobijou Inc. which is manufactured by Ellelux.
Like other toxin brands, Ellelux removes deep forehead wrinkles, frown lines, turkey neck caused by platysmal streaks, crow’s feet.
Ellelux can also effectively combat excessive sweating.
Ellelux belongs to the low-budget botulinum toxin segment and can be purchased much cheaper than its more well-known competitors.
11. Wellstox
Wellstox, like Ellelux, is a new brand produced and distributed by the Korean biotechnology company WELLSPHARMTECH CO., LTD. According to the company, Wellstox has shown excellent product stability in testing.
The advantages, as in the case of Ellelux, include a low price, for which you still get a high-quality and effective product.
How to choose a Korean botox brand?
It can be difficult to know which product is best for you. The long list of Korean toxin options available can be overwhelming, but as part of our review, we have tried to cover Most Popular Korean Brands of botox Injections in 2023. Recently, more and more new brands of Korean botox have been entering the market. They range from the popular ones like Botulax, Nabota, Liztox and Innotox to the new but already well-known among practitioners like Rentox, Toxsta and others.
On the one hand, healthy competition should favorably affect the pricing policy of manufacturing companies and distributors. The clinical nuances of each drug, the dosage in the vial, shelf life, price, and most importantly – the effectiveness and the minimum number of adverse events – all this combination of properties will allow you to find “your drug” that meets all requests.
On the other hand, the Korean brands of Botox, which today occupy a leading position, have a certain medical background, including in the form of statistics on immunogenicity and adverse reactions. Registration of new indications for them is not fast, because it is preceded by serious clinical studies with confirmation of efficacy and safety. All this cannot but add confidence when working with such brands.
That being said, each brand of Botox does the same job despite the different names. If the correct dosage is applied and proper care is provided during the procedure, each brand of Botox should achieve the same long-term result. Thus, it is a mistake to believe that a particular brand of Botox will result in a flawed appearance. All errors are attributed to the practitioner, not the product.
Using any of the Korean botox brands discussed in this article can lead to great aesthetics and increased self-confidence. Botox injections are a very positive cosmetic procedure that, when properly dosed, will reward patients with a symmetrical, natural, and younger appearance. In short, Korean botox is safe and reliable.
All the brand you can buy.
Is Korean Botox Safe?
There are three main Korean suppliers of botulinum toxin products: Medytox, Hugel, and Daewoong Pharmaceuticals. The authentic products of these three suppliers are maximally safe.
Moreover, Korean botox products are known for their high quality and extra purity. If you use the Korean botulinum toxin from a reliable producer, you do not expect extraordinary side effects. However, be aware of no-name products or fake products.
What brand of Botox lasts the longest?
The persistence of the effect of “beauty shots” depends on the individual characteristics of the patient’s body. Statistically, wrinkles and “creases” are smoothed out for 3-4 months. After that, the procedure should be repeated if desired.
The duration of the effect of the American Botox is 4-6 months. The Korean brands like Botulax also claim a duration of effect of up to 6 months.
Features of Korean Botox Products
Clinical trials show that Korean botox products are identical to American ones. However, three main features differentiate Korean botox products on the market.
- High Quality
South Korea appears at the epicenter of the Asian technological boom. As the result, the country adopted numerous modern technologies in many industries. The Korean beauty industry is proud of its modern technological background, so they claim its products are of the highest quality.
- Affordable Price
Due to the lower production costs and lower salaries in South Korea, the production price of Korean botox products is lower. On the market, it can make half of the identical American botox products.
- Long Lasting Effect
Korean manufacturers declare their products have a long-lasting effect. Really, during the recent decade, the effect of standard botox injections increased by 1\3 – for example, from 4 months to 6 at the same face zone and with the same product. However, critical trials see no difference between the effect duration for Korean and American botox products.
How to store botox?
According to the recommendations of most manufacturers of Korean botox, the toxin should be stored in the refrigerator at a temperature of 2-8℃ until diluted. There are a number of studies that confirm the safety of storing botox in the refrigerator at 2-8℃.
As for the storage of the diluted solution, it should be in a refrigerator at a temperature of 2℃ to 8℃. In such conditions, according to the manufacturer’s instructions, the shelf life of diluted botox is only 24 hours.
Repeated freezing and thawing of an already diluted botox solution is not permissible, because. molecules of toxins can be damaged by ice crystals (according to studies, in this case, about 69.8% of the activity of botulinum toxin is lost).
To store botox in your home, keep the product covered and store between 2 and 8 degrees Celsius. Be sure to use the product 36 months from the date of manufacture.
Don’t be alarmed if your vial looks empty. At the bottom of the vial, a white powder is visible, which must be dissolved in saline.
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