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Xeomin 100U is a premium botulinum toxin type A created by Merz Pharmaceuticals and supplied in authentic Korean-market packaging. It’s designed to soften the appearance of expression lines by temporarily relaxing targeted facial muscles, helping the skin look smoother and more refreshed. With its uniquely purified, additive-free formulation, Xeomin delivers natural-looking results without heaviness, making it a popular choice for clients who want a subtle, refined enhancement.
Main Benefits of Xeomin 100U
Highly Purified Formula
Made without complexing proteins for a clean, streamlined composition.
Natural Expression
Softens lines while keeping natural facial movement.
Fast Visible Improvement
Smoother-looking skin often appears within 3–4 days.
Consistent Performance
Provides steady, reliable cosmetic results.
Refined Smoothing
Helps reduce the look of common expression lines.
Lightweight Finish
Feels natural on the skin without heaviness.
Indications
- Softening the appearance of frown lines
- Reducing visible forehead creases
- Smoothing crow’s feet around the eyes
- Minimizing expression-related lines for a fresher look
- Enhancing overall facial smoothness
- Supporting a more relaxed, refined appearance
How is Xeomin made
Xeomin is produced by Merz Pharmaceuticals using a highly controlled manufacturing process that isolates botulinum toxin type A from Clostridium botulinum. During production, the active neurotoxin is carefully purified to remove complexing proteins, resulting in a clean, lightweight 150 kD molecule.
This purification method is what gives Xeomin its well-known “additive-free” composition. After purification, the toxin is stabilized, dried into a fine powder, and sealed in sterile vials to maintain quality and consistency until reconstitution.
What Xeomin 100U is made of
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Clostridium Botulinum Neurotoxin Type A (100U)
A purified 150 kD neurotoxin used to relax targeted facial muscles, helping soften the look of dynamic expression lines.
Mechanism of action
Xeomin works by temporarily reducing activity in the facial muscles that create dynamic expression lines. When these muscles relax, the skin above them appears smoother and less creased. Its purified neurotoxin formulation interacts at the nerve–muscle junction to lessen repeated contractions, which helps soften the look of wrinkles that form from frowning, squinting, or other expressions.
Why does Xeomin 100U look Empty? (Video Explanation)
Product preparation
Before use, Xeomin 100U must be reconstituted with preservative-free 0.9% sterile saline (sodium chloride injection) to prepare it for cosmetic application. It is supplied as a fine, freeze-dried powder in a clear glass vial containing 100 units. The powder may look nearly invisible or appear as a thin layer on the vial bottom, which is normal for this product.
Preparation Steps:
Bring the Xeomin 100U vial to room temperature and inspect it. The powder should appear as a very fine, almost invisible layer inside the vial.
With a sterile syringe, slowly introduce the required amount of preservative-free 0.9% saline into the vial (refer to the appropriate dilution chart for guidance).
Gently swirl or invert the vial until the powder fully dissolves — avoid shaking vigorously. The solution should become clear and particle-free.
Use the reconstituted product within 24 hours and store it in the refrigerator at 2–8°C during this period. Do not freeze after reconstitution.
How to dilute Xeomin 100U?
Xeomin 100U is supplied as a fine, freeze-dried powder containing 100 units of Botulinum toxin type A. It must be diluted with preservative-free 0.9% sterile saline before use.
Note: The powder is extremely fine and may look almost invisible in the vial. This is normal — all units are present.
Step-by-Step Dilution Instructions
Inspect the Xeomin 100U vial. The powder will appear as a thin, nearly invisible layer at the bottom or walls of the vial.
Draw the chosen amount of preservative-free 0.9% Sodium Chloride into a sterile syringe, based on the dilution chart above.
Slowly inject the saline into the vial. Allow the natural vacuum to pull in the solution where applicable.
Gently swirl or invert the vial to mix. Do not shake vigorously. The solution should become clear and colorless.
Store the reconstituted solution in a refrigerator at 2–8°C and use within 24 hours. Do not freeze after reconstitution.
Treatment areas
Glabellar Lines (frown lines between the brows)
Forehead Lines that appear with expression
Crow’s Feet around the outer corners of the eyes
Bunny Lines along the sides of the nose
Chin Dimpling caused by overactive mentalis movement
Areas of Strong Expression that create noticeable dynamic lines
Dosage and technique
Xeomin 100U is applied in small, precise amounts depending on the depth and strength of the expression lines being treated. The number of units can vary based on the area and the desired level of softening.
The reconstituted solution is placed into targeted facial points using a fine sterile needle. Each point receives a controlled amount of product to gently reduce the movement that creates dynamic wrinkles. The technique focuses on even placement and balanced distribution, helping achieve smooth, natural-looking results without over-treating.
Post-treatment
Avoid touching or rubbing the treated areas for several hours to prevent disrupting the product placement.
Keep your head upright for the first few hours and avoid lying flat immediately afterward.
Refrain from intense exercise, saunas, or heat exposure for the rest of the day.
Give the product time to settle — visible smoothing typically begins within a few days.
Mild redness or tightness may occur temporarily and usually settles on its own.
Course of Treatments
How quickly will the result appear?
Before & Afters
What's Inside
Xeomin 100 Units Vial
One vial containing 100 units of Clostridium Botulinum Neurotoxin Type A (150 kD) in a fine, freeze-dried powder form.Instruction Leaflet
Includes manufacturer details on product composition, reconstitution guidelines, and storage information.
FAQ
Xeomin 100U is a purified botulinum toxin type A used to soften the look of dynamic facial lines for a smoother, refreshed appearance.
Most people enjoy smoother-looking skin for about 3 to 4 months, depending on natural facial movement.
Initial softening typically appears in 3–4 days, with full results in about 1–2 weeks.
The powder is extremely fine and often looks nearly invisible inside the vial — this is completely normal.
Xeomin must be mixed with preservative-free 0.9% sterile saline before use. The amount depends on the desired units per 0.1 mL.
How to properly store
Unreconstituted Xeomin can be kept at room temperature in its original packaging. No refrigeration is needed before dilution.
After mixing with preservative-free saline, store the reconstituted solution in a refrigerator at 2–8°C.
Use the prepared solution within 24 hours.
Keep the vial protected from direct sunlight and do not freeze after reconstitution.
Always handle and store the product according to standard sterile handling guidelines.
Xeomin 100 is intended for use by licensed medical professionals only. Improper storage or handling may affect product quality. We are not responsible for outcomes resulting from misuse, improper administration, or storage outside the recommended conditions.
Product Benefits This product is excellent. I always seek products that’s pure. Results are soo natural
Products shows better results than other toxins I use
Product Benefits The best
Age 39
Won’t use anything else. No fillers. Lasts long.
I love Xeomin. Won’t use anything else. Great price!
Great
I’m looking forward to using this one! I ordered Dysport last time and am enjoying it.