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Main Benefits
High purity and safety
Produced with UPHEC purification technology, ensuring no residual BDDE and reduced risk of allergic reactions or swelling.
Long-lasting results
With a concentration of 24 mg/mL cross-linked HA, effects can last between 12–18 months.
Comfortable treatment
Contains 0.3% lidocaine to minimize discomfort during and after injection.
Versatile use
Suitable for correcting deep skin folds, lip augmentation, and facial contouring.
Clinically reliable
Non-animal origin hyaluronic acid with a high level of stability for consistent outcomes.
Trusted quality
Manufactured by Newmedic Co., Ltd. in South Korea under strict international safety standards.
Rejeunesse Deep is a premium dermal filler designed for mid to deep dermis injections, it is ideal for correcting deep skin folds, enhancing lip volume, and refining overall facial contours.
Many Korean celebrities are known to have used this filler, because of this it has become a leading product in the beauty industry. It contains hyaluronic acid at a concentration of 24mg/ml and has a long lasting lip augmentation effect. In addition, Rejeunesse Deep can also be applied with a Hyaluron pen, providing flexibility in treatment options.
Indications
Rejeunesse Deep is formulated for injections into the mid to deep dermis, making it suitable for treating areas that need stronger support and visible correction. It is commonly used for:
Deep wrinkles and folds such as nasolabial folds, marionette lines, and other pronounced creases.
Lips, to restore lost volume, improve shape, and create fuller, more defined lips.
Facial contouring, enhancing cheekbones, refining the chin or jawline, and improving overall balance of facial features.
Nose correction, used for non-surgical rhinoplasty to lift, smooth, or refine nasal shape.
Intimate area correction for restoring volume and structure in delicate areas.
Active Ingredients
Hyaluronic Acid (24 mg/ml)
A high-purity, non-animal derived HA that restores lost volume, smooths wrinkles, and hydrates the skin.
Lidocaine (0.3%)
A local anesthetic included in the formula to minimize pain and discomfort during and after injection.
Rejeunesse Deep is produced using the UPHEC purification technology, which ensures exceptionally high purity of the hyaluronic acid. This process removes impurities and significantly reduces endotoxin levels, lowering the risk of allergic reactions and swelling.
The filler contains no residual BDDE, making it safer for use compared to many other cross-linked fillers. Combined with its non-animal origin hyaluronic acid and strict manufacturing standards, Rejeunesse Deep is recognized as a reliable and safe option for aesthetic treatments.
Mechanism of Action
Rejeunesse Deep works by using cross-linked hyaluronic acid (HA) to restore volume beneath the skin. When injected into the mid to deep dermis, the HA attracts and binds water molecules, which helps to:
Fill deep wrinkles and folds by adding structure and support.
Enhance volume in areas like the lips, cheeks, or chin.
Improve skin elasticity by supporting collagen and elastin in the surrounding tissues.
The cross-linking technology makes the gel more stable, slowing down natural breakdown of HA and extending the effects for 12–18 months.
What Makes Rejeunesse Deep Different?
Rejeunesse Deep stands out for its high level of purity, achieved through the advanced UPHEC purification technology. This process removes impurities, lowers endotoxin levels, and ensures there are no residual BDDE particles, which helps minimize the risk of allergic reactions and swelling.
Unlike many fillers, Rejeunesse Deep offers long-lasting results of 12–18 months, thanks to its stable cross-linked hyaluronic acid structure. Its monophasic gel consistency allows for smooth and even distribution under the skin, delivering natural-looking volume and correction.
Comfort is another key advantage. With 0.3% lidocaine already included in the formulation, procedures are less painful and more comfortable for both the client and the practitioner.
Finally, Rejeunesse Deep is recognized for its versatility. It can effectively treat deep wrinkles and folds, enhance lip volume, refine facial contours, and even be used for non-surgical nose corrections. Other products in the Rejeunesse line are Rejeunesse Fine and Rejeunesse Shape.
Treatment Areas
Rejeunesse Deep is injected into the mid to deep dermis and is suitable for restoring volume and correcting deeper imperfections. It is commonly used for:
Deep wrinkles and folds – including nasolabial folds and marionette lines
Lips – adding volume, enhancing shape, and restoring definition
Facial contouring – cheeks, chin, and jawline refinement
Nose correction – non-surgical rhinoplasty for shape adjustment
Forehead – smoothing deep horizontal lines and restoring fullness
Preparations Before Use
Before treatment, the skin should be thoroughly cleansed and disinfected to reduce the risk of infection.
The syringe is pre-filled and ready to use, requiring no mixing or reconstitution.
Always check the packaging integrity, expiration date, and sterility before opening. The included 27G needles must be used only if the package is undamaged and sterile.
Dosage and Technique of Application
The amount of Rejeunesse Deep required will depend on the treatment area, depth of wrinkles, and the level of correction desired. Injections are administered into the mid to deep dermis using the supplied 27G needles.
Common techniques include linear threading, serial puncture, and fan technique, which allow for even distribution of the gel and natural-looking results. The filler should be injected slowly and with controlled pressure to ensure accurate placement and minimize discomfort.
What to Do After Injection Sessions?
- Avoid touching or pressing the treated area for several hours after injection.
- Do not apply makeup for at least 12 hours.
- Avoid heat exposure such as saunas, hot baths, or direct sunlight for the first few days.
- Refrain from alcohol and strenuous exercise for 24–48 hours, as these may increase swelling or bruising.
- Do not undergo other cosmetic treatments (e.g., chemical peels, laser therapy) on the treated area until advised by a professional.
- Mild redness, swelling, or bruising may occur but usually resolves within a few days.
Course of Treatments
How quickly will the result appear?
Before and After
What's Inside
Each Rejeunesse Deep package contains:
1 pre-filled syringe (1.1 mL)
2 sterile 27G needles
Product insert with usage and safety instructions
The product is supplied in a sterile, sealed package and is intended for single-use only.
FAQ
The results of Rejeunesse Deep treatment last 12 to 18 months, depending on skin type, lifestyle, and the treatment area.
Results are visible immediately after injection and continue to improve as the filler integrates naturally with the skin.
Rejeunesse Deep is used for lip volumization, correction of deep skin folds, and facial contouring. It can also be applied for the correction of nasolabial furrows, medium to deep wrinkles, and reshaping of the lips.
It is injected into the mid to deep dermis where cross-linked hyaluronic acid restores volume, smooths lines, and enhances facial features. The addition of 0.3% lidocaine ensures a more comfortable treatment experience.
Yes. Rejeunesse is a hyaluronic acid-based filler known for its high purity, safety, and cross-linked structure, which provide natural-looking results that last longer. Its smooth monophasic consistency allows for even distribution, making it especially effective for lip augmentation and contouring.
Yes. It is made with non-animal origin hyaluronic acid and processed with UPHEC purification technology, ensuring no residual BDDE and low endotoxin levels. This minimizes the risk of allergic reactions and swelling.
Yes, Rejeunesse Deep is available through our wholesale program. This Korean HA filler targets medium to deep dermal layers with results lasting over 12 months. Wholesale purchasing enables you to maintain adequate inventory while managing costs effectively. To access wholesale rates, complete our Wholesale Application to get started.
How to Store
Store in a cool, dry place at a controlled room temperature between 2°C and 25°C
Do not freeze or heat the product, as this may damage the gel structure
Keep the syringe in its original sterile packaging until use
Protect from direct sunlight
Single-use only – do not reuse
Do not use if the packaging is opened or the seal is damaged
This product is intended for use by licensed medical professionals only. We accept no responsibility for adverse effects or complications resulting from improper handling, self-administration, or use by unqualified individuals. No compensation will be provided for products that are damaged, wasted, or misused.
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Product Benefits Add nice volume to my lips
Age 41
Very user friendly and easy to apply
Product Benefits Fuller lips, added volume to lines
Age 44
Does what it says. Great option for hya pen.
Wonderful
Amazing product very easy to use with the hyaluron pen.